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• W2085991844 abstract "ABSTRACT Vesicular stomatitis virus (VSV) is a prototype nonsegmented, negative-sense virus used to examine viral functions of a broad family of viruses, including human pathogens. Here we demonstrate that S 2 VSV, an isolate with a small plaque phenotype compared to other Indiana strain viruses, has a transcription defect resulting in an altered pattern and rapid decline of transcription. The S 2 VSV transcription gradient is dominant over the wild-type transcription in a coinfection. This is the first characterization of an altered gradient of transcription not dependent on RNA template sequence or host response and may provide insight into new approaches to viral attenuation." @default.
• W2085991844 created "2016-06-24" @default.
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• W2085991844 date "2012-08-15" @default.
• W2085991844 modified "2023-10-16" @default.
• W2085991844 title "A Vesiculovirus Showing a Steepened Transcription Gradient and Dominant <i>trans</i> -Repression of Virus Transcription" @default.
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• W2085991844 doi "https://doi.org/10.1128/jvi.00358-12" @default.
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