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- W2085993487 abstract "Deux cas de complications graves survenues après injection de peroxyde d'hydrogène sous pression dans des zones d'attrition musculaire consécutives à des blessures de guerre sont rapportés. Dans les deux cas, l'injection de peroxyde d'hydrogène s'est accompagnée d'une tachypnée avec désaturation artérielle profonde et perception d'un bruit de rouet précordial, suivie dans un cas d'une hémiplégie par embolie gazeuse artérielle paradoxale et dans l'autre cas d'un œdème pulmonaire lésionnel. Les deux cas ont évolué favorablement sous oxygénothérapie hyperbare. La libération d'oxygène gazeux sous l'effet des catalases tissulaires et le pouvoir peroxydasique membranaire du peroxyde d'hydrogène expliquent ce type de complications. L'injection de peroxyde d'hydrogène sous forte pression dans une cavité close ou presque close doit donc être formellement proscrite. Two cases of severe complications due to injection of hydrogen peroxide under pressure into areas of muscular attrition in war wounds are reported. In both cases the administration of hydrogen peroxide was associated with tachypnoea, with major arterial desaturation and a precordial « mill-wheelmurmur was heard. In one case, these symptoms were followed by hemiplegia caused by paradoxical arterial gas embolism, and in the other case by a pulmonary oedema confirmed by computerized tomography. Both patients recovered under hyperbaric oxygen therapy. The release of gaseous oxygen under the effect of tissue catalase and the membrane peroxydasic activity of hydrogen peroxide initiate such complications. The injection of hydrogen peroxide under pressure into a closed or partially closed cavity should therefore be strictly prohibited." @default.
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- W2085993487 title "Risques de l'irrigation au peroxyde d'hydrogène en chirurgie de guerre" @default.
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- W2085993487 doi "https://doi.org/10.1016/s0750-7658(05)80736-1" @default.
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