FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085996989> ?p ?o ?g. }

• W2085996989 endingPage "1054" @default.
• W2085996989 startingPage "1048" @default.
• W2085996989 abstract "We have recently reported that intake of soya protein isolate (SPI) inhibited the DNA-binding activities of hepatic thyroid hormone receptor (TR). The genes for acetyl-CoA carboxylase (ACC), a rate-limiting enzyme in fatty acid synthesis, contain the thyroid hormone response element in their promoters and are regulated by TR. The present study has examined the effect oflong-term feeding of SPI and soya isoflavones (ISF) on the gene expression and protein phosphorylation of different ACC isoforms in different tissues and plasma triacylglycerol (TAG) levels in rats. Sprague-Dawley female rats were fed diets containing 20% casein or alcohol-washed SPI with or without supplemental ISF for 70, 190 and 310d. SPI intake significantly reduced plasma TAG concentrations compared with casein, whereas supplemental ISF had no effect. Hepatic ACCα and ACCβ mRNA abundance and protein content were markedly lowerin the rats fed SPI than in those fed casein. The protein contents of ACCα in the kidneyand ACCβ, the predominant isoform in the heart and kidney, were unchanged by dietary SPI.The ratios of phospho-ACCα/ACCα and phospho-ACCβ/ACCβ were not differentamong dietary groups in all tissues measured. The present study demonstrates that ingestion ofSPI decreases plasma TAG level and down-regulates ACCα and ACCβ gene expression in the liver but not in the heart and kidney. The results indicate that the effect of SPI is tissue-specific and that alteration of ACC gene expression rather than phosphorylation status may play a major role in the regulation of ACC activities by soya proteins." @default.
• W2085996989 created "2016-06-24" @default.
• W2085996989 creator A5006119861 @default.
• W2085996989 creator A5011297388 @default.
• W2085996989 creator A5040462534 @default.
• W2085996989 creator A5056858393 @default.
• W2085996989 creator A5074878046 @default.
• W2085996989 creator A5085262899 @default.
• W2085996989 creator A5091373580 @default.
• W2085996989 date "2006-06-01" @default.
• W2085996989 modified "2023-09-26" @default.
• W2085996989 title "Tissue-specific regulation of acetyl-CoA carboxylase gene expression by dietary soya protein isolate in rats" @default.
• W2085996989 cites W1576899066 @default.
• W2085996989 cites W1628693640 @default.
• W2085996989 cites W1805124418 @default.
• W2085996989 cites W1822012721 @default.
• W2085996989 cites W1831301545 @default.
• W2085996989 cites W1906861713 @default.
• W2085996989 cites W1907247569 @default.
• W2085996989 cites W1941200497 @default.
• W2085996989 cites W1958429861 @default.
• W2085996989 cites W1964122705 @default.
• W2085996989 cites W1971910288 @default.
• W2085996989 cites W1973136663 @default.
• W2085996989 cites W1974442351 @default.
• W2085996989 cites W1975654782 @default.
• W2085996989 cites W1982126966 @default.
• W2085996989 cites W1987521284 @default.
• W2085996989 cites W1998732486 @default.
• W2085996989 cites W2022996249 @default.
• W2085996989 cites W2039501269 @default.
• W2085996989 cites W2040871554 @default.
• W2085996989 cites W2042444876 @default.
• W2085996989 cites W2061327030 @default.
• W2085996989 cites W2062470598 @default.
• W2085996989 cites W2068515260 @default.
• W2085996989 cites W2069095270 @default.
• W2085996989 cites W2071373998 @default.
• W2085996989 cites W2093555922 @default.
• W2085996989 cites W2109769701 @default.
• W2085996989 cites W2111522158 @default.
• W2085996989 cites W2114853986 @default.
• W2085996989 cites W2120400493 @default.
• W2085996989 cites W2125066198 @default.
• W2085996989 cites W2130755410 @default.
• W2085996989 cites W2131207742 @default.
• W2085996989 cites W2134703037 @default.
• W2085996989 cites W2138659411 @default.
• W2085996989 cites W2142109898 @default.
• W2085996989 cites W2147512668 @default.
• W2085996989 cites W2161878796 @default.
• W2085996989 cites W2169599724 @default.
• W2085996989 cites W2333028705 @default.
• W2085996989 doi "https://doi.org/10.1079/bjn20061776" @default.
• W2085996989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16768825" @default.
• W2085996989 hasPublicationYear "2006" @default.
• W2085996989 type Work @default.
• W2085996989 sameAs 2085996989 @default.
• W2085996989 citedByCount "11" @default.
• W2085996989 countsByYear W20859969892014 @default.
• W2085996989 countsByYear W20859969892015 @default.
• W2085996989 countsByYear W20859969892021 @default.
• W2085996989 countsByYear W20859969892022 @default.
• W2085996989 crossrefType "journal-article" @default.
• W2085996989 hasAuthorship W2085996989A5006119861 @default.
• W2085996989 hasAuthorship W2085996989A5011297388 @default.
• W2085996989 hasAuthorship W2085996989A5040462534 @default.
• W2085996989 hasAuthorship W2085996989A5056858393 @default.
• W2085996989 hasAuthorship W2085996989A5074878046 @default.
• W2085996989 hasAuthorship W2085996989A5085262899 @default.
• W2085996989 hasAuthorship W2085996989A5091373580 @default.
• W2085996989 hasBestOaLocation W20859969891 @default.
• W2085996989 hasConcept C104317684 @default.
• W2085996989 hasConcept C126322002 @default.
• W2085996989 hasConcept C134018914 @default.
• W2085996989 hasConcept C140137476 @default.
• W2085996989 hasConcept C150194340 @default.
• W2085996989 hasConcept C181199279 @default.
• W2085996989 hasConcept C185592680 @default.
• W2085996989 hasConcept C2776142715 @default.
• W2085996989 hasConcept C2776941171 @default.
• W2085996989 hasConcept C2779318131 @default.
• W2085996989 hasConcept C543025807 @default.
• W2085996989 hasConcept C55493867 @default.
• W2085996989 hasConcept C71924100 @default.
• W2085996989 hasConcept C86803240 @default.
• W2085996989 hasConceptScore W2085996989C104317684 @default.
• W2085996989 hasConceptScore W2085996989C126322002 @default.
• W2085996989 hasConceptScore W2085996989C134018914 @default.
• W2085996989 hasConceptScore W2085996989C140137476 @default.
• W2085996989 hasConceptScore W2085996989C150194340 @default.
• W2085996989 hasConceptScore W2085996989C181199279 @default.
• W2085996989 hasConceptScore W2085996989C185592680 @default.
• W2085996989 hasConceptScore W2085996989C2776142715 @default.
• W2085996989 hasConceptScore W2085996989C2776941171 @default.
• W2085996989 hasConceptScore W2085996989C2779318131 @default.
• W2085996989 hasConceptScore W2085996989C543025807 @default.
• W2085996989 hasConceptScore W2085996989C55493867 @default.

• next