Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086041369> ?p ?o ?g. }
- W2086041369 endingPage "459" @default.
- W2086041369 startingPage "454" @default.
- W2086041369 abstract "1 The serum and hepatic lipid concentrations were investigated in rats made nephrotic with a single intraperitoneal injection of cisplatin (6 mg kg -1 b.wt.). 2 The serum creatinine and urea concentrations were estimated as indices of nephrotoxicity, and the serum total bilirubin level as a liver function test. 3 The fasting serum total cholesterol, triglycerides (TG) and the cholesterol fractions associated with the various lipoproteins, as well as hepatic cholesterol and TG contents were also measured, following 5, 10 and 15 days from the cisplatin treatment. 4 The results revealed that on day 5 both serum creatinine and urea concentrations were significantly (P50.01) increased, indicating the peak of nephrotoxicity, with no injurious effects on the liver as indicated by the unaltered serum bilirubin concentration. 5 The nephrotoxicity was accompanied by significant elevations in serum total cholesterol and TG concentrations by 49 and 42%, respectively, with significant (P50.05) correlations between the serum cholesterol and TG concentrations versus the serum urea (r=0.68 and r=0.60, respectively). 6 Among the estimated lipoproteins, very low density lipoprotein (VLDL) cholesterol was severely increased to more than twofold with no severe changes in LDL or HDL-cholesterol fractions. On day 5 the liver also showed significant accumulation of TG with no change in the cholesterol content. 7 Animals killed 10 or 15 days post-cisplatin treatment had all the perturbed parameters returned to the normal levels. 8 The present results indicated that rats exposed to a single cisplatin injection exhibit acute reversible nephrosis on day 5 which was accompanied by dyslipidaemia and accumulated liver TG." @default.
- W2086041369 created "2016-06-24" @default.
- W2086041369 creator A5031981708 @default.
- W2086041369 creator A5034272883 @default.
- W2086041369 creator A5063646488 @default.
- W2086041369 date "1999-07-01" @default.
- W2086041369 modified "2023-10-14" @default.
- W2086041369 title "Hyperlipidaemia in cisplatin-induced nephrotic rats" @default.
- W2086041369 cites W1963718159 @default.
- W2086041369 cites W1965252862 @default.
- W2086041369 cites W1966090266 @default.
- W2086041369 cites W1978078272 @default.
- W2086041369 cites W1978780007 @default.
- W2086041369 cites W1979500804 @default.
- W2086041369 cites W1980611267 @default.
- W2086041369 cites W1989256522 @default.
- W2086041369 cites W1994295837 @default.
- W2086041369 cites W2021501022 @default.
- W2086041369 cites W2027269602 @default.
- W2086041369 cites W2031696517 @default.
- W2086041369 cites W2032700523 @default.
- W2086041369 cites W2033539955 @default.
- W2086041369 cites W2043035737 @default.
- W2086041369 cites W2045096999 @default.
- W2086041369 cites W2046378907 @default.
- W2086041369 cites W2047808622 @default.
- W2086041369 cites W2047941942 @default.
- W2086041369 cites W2050525994 @default.
- W2086041369 cites W2056787972 @default.
- W2086041369 cites W2075798525 @default.
- W2086041369 cites W2084507256 @default.
- W2086041369 cites W2091179723 @default.
- W2086041369 cites W2092829919 @default.
- W2086041369 cites W2093392604 @default.
- W2086041369 cites W2329781036 @default.
- W2086041369 cites W2387777486 @default.
- W2086041369 cites W4236410182 @default.
- W2086041369 cites W67746198 @default.
- W2086041369 doi "https://doi.org/10.1191/096032799678840255" @default.
- W2086041369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10454078" @default.
- W2086041369 hasPublicationYear "1999" @default.
- W2086041369 type Work @default.
- W2086041369 sameAs 2086041369 @default.
- W2086041369 citedByCount "23" @default.
- W2086041369 countsByYear W20860413692012 @default.
- W2086041369 countsByYear W20860413692015 @default.
- W2086041369 countsByYear W20860413692016 @default.
- W2086041369 countsByYear W20860413692017 @default.
- W2086041369 countsByYear W20860413692020 @default.
- W2086041369 countsByYear W20860413692023 @default.
- W2086041369 crossrefType "journal-article" @default.
- W2086041369 hasAuthorship W2086041369A5031981708 @default.
- W2086041369 hasAuthorship W2086041369A5034272883 @default.
- W2086041369 hasAuthorship W2086041369A5063646488 @default.
- W2086041369 hasConcept C126189478 @default.
- W2086041369 hasConcept C126322002 @default.
- W2086041369 hasConcept C134018914 @default.
- W2086041369 hasConcept C185592680 @default.
- W2086041369 hasConcept C2777513400 @default.
- W2086041369 hasConcept C2778163477 @default.
- W2086041369 hasConcept C2780072125 @default.
- W2086041369 hasConcept C2780159080 @default.
- W2086041369 hasConcept C2780306776 @default.
- W2086041369 hasConcept C2780365088 @default.
- W2086041369 hasConcept C2781175652 @default.
- W2086041369 hasConcept C29730261 @default.
- W2086041369 hasConcept C55493867 @default.
- W2086041369 hasConcept C71924100 @default.
- W2086041369 hasConcept C8243546 @default.
- W2086041369 hasConceptScore W2086041369C126189478 @default.
- W2086041369 hasConceptScore W2086041369C126322002 @default.
- W2086041369 hasConceptScore W2086041369C134018914 @default.
- W2086041369 hasConceptScore W2086041369C185592680 @default.
- W2086041369 hasConceptScore W2086041369C2777513400 @default.
- W2086041369 hasConceptScore W2086041369C2778163477 @default.
- W2086041369 hasConceptScore W2086041369C2780072125 @default.
- W2086041369 hasConceptScore W2086041369C2780159080 @default.
- W2086041369 hasConceptScore W2086041369C2780306776 @default.
- W2086041369 hasConceptScore W2086041369C2780365088 @default.
- W2086041369 hasConceptScore W2086041369C2781175652 @default.
- W2086041369 hasConceptScore W2086041369C29730261 @default.
- W2086041369 hasConceptScore W2086041369C55493867 @default.
- W2086041369 hasConceptScore W2086041369C71924100 @default.
- W2086041369 hasConceptScore W2086041369C8243546 @default.
- W2086041369 hasIssue "7" @default.
- W2086041369 hasLocation W20860413691 @default.
- W2086041369 hasLocation W20860413692 @default.
- W2086041369 hasOpenAccess W2086041369 @default.
- W2086041369 hasPrimaryLocation W20860413691 @default.
- W2086041369 hasRelatedWork W1976602105 @default.
- W2086041369 hasRelatedWork W1999568358 @default.
- W2086041369 hasRelatedWork W2005812619 @default.
- W2086041369 hasRelatedWork W2005998106 @default.
- W2086041369 hasRelatedWork W2037776442 @default.
- W2086041369 hasRelatedWork W2086041369 @default.
- W2086041369 hasRelatedWork W2129790693 @default.
- W2086041369 hasRelatedWork W2157000830 @default.
- W2086041369 hasRelatedWork W2157155183 @default.