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- W2086069144 abstract "Patients with severe staphylococcal infections that have not responded to the usual antimicrobial therapy are common in present-day hospital practice. It is hoped that the data to be presented regarding the relative efficacy and toxicity of ristocetin, vancomycin, and kanamycin will help the clinician to make a decision about further antimicrobial therapy for these patients. It was possible to alternate the use of ristocetin, vancomycin, and kanamycin in a group of seriously ill patients because the three drugs were discovered within such a short time of each other that no one of them had an opportunity to be established as the drug of choice in severe staphylococcic infections.<sup>1-3</sup>Each of these three antibiotics acted as a control for the others in the study, and this circumvented the necessity of extrapolating opinions regarding their effectiveness in severe infections from actual experience with milder, non-life-threatening infections. <h3>Materials and Methods</h3><h3>Drugs.</h3> —Ristocetin" @default.
- W2086069144 created "2016-06-24" @default.
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- W2086069144 date "1960-08-01" @default.
- W2086069144 modified "2023-10-16" @default.
- W2086069144 title "Comparative Clinical Effectiveness and Toxicity of Vancomycin, Ristocetin, and Kanamycin" @default.
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- W2086069144 doi "https://doi.org/10.1001/archinte.1960.03820020019005" @default.
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