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• W2086101293 abstract "An effective approach towards optimal development strategy is to use the quality by design principle. However, this approach can first be implemented when possible risks impacting critical quality attributes are defined and interactions between those are fully understood. The objective of this study was to identify critical variables that affect the final modified release product performance using a risk management approach with supporting statistical tool. After risk ranking and filtering a full mixed factorial experimental design of coating experiments was performed. Experimental design clearly indicated that studied critical processes parameters have a great impact on coat integrity and hence on drug release." @default.
• W2086101293 created "2016-06-24" @default.
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• W2086101293 date "2010-01-21" @default.
• W2086101293 modified "2023-10-03" @default.
• W2086101293 title "Building quality into a coating process" @default.
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• W2086101293 doi "https://doi.org/10.3109/10837450902882377" @default.
• W2086101293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19694502" @default.
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