Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086144613> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2086144613 endingPage "109" @default.
- W2086144613 startingPage "101" @default.
- W2086144613 abstract "The effects of thiol compounds on insulin release were studied in microdissected pancreatic islets of non-inbred ob/ob mice. In control experiments the reactivity of thiols against 6,6′-dithiodinicotinic acid and the degradation of mouse insulin were measured. At a concentration of 0.1 mM, 1-thio-D-glucose or reduced glutathione potentiated the insulin-releasing action of 10 mM D-glucose without affecting glucose oxidation. When tested at a concentration equivalent to about 0.1 mM reactive thiol, dextran-linked L-cysteine also potentiated the glucose-induced insulin secretion. In microperifusion experiments the insulin-releasing action of 1-thio-D-glucose was found to exhibit a rapid onset followed by a decline of the secretory rate to values lower than those observed with 10 mM D-glucose alone. No thiol stimulated insulin release in the absence of glucose. It is suggested that thiol compounds stimulate insulin release by splitting membrane disulphides in the β-cells." @default.
- W2086144613 created "2016-06-24" @default.
- W2086144613 creator A5008841181 @default.
- W2086144613 creator A5030356944 @default.
- W2086144613 creator A5030923663 @default.
- W2086144613 creator A5041081446 @default.
- W2086144613 creator A5086940680 @default.
- W2086144613 date "1975-05-05" @default.
- W2086144613 modified "2023-10-14" @default.
- W2086144613 title "Stimulation of insulin release by thiols" @default.
- W2086144613 cites W1746607743 @default.
- W2086144613 cites W1750096759 @default.
- W2086144613 cites W1983150993 @default.
- W2086144613 cites W1999986826 @default.
- W2086144613 cites W2007529384 @default.
- W2086144613 cites W2047548269 @default.
- W2086144613 cites W2083550236 @default.
- W2086144613 cites W2087409662 @default.
- W2086144613 cites W2167677553 @default.
- W2086144613 doi "https://doi.org/10.1016/0304-4165(75)90170-1" @default.
- W2086144613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1092370" @default.
- W2086144613 hasPublicationYear "1975" @default.
- W2086144613 type Work @default.
- W2086144613 sameAs 2086144613 @default.
- W2086144613 citedByCount "19" @default.
- W2086144613 countsByYear W20861446132012 @default.
- W2086144613 crossrefType "journal-article" @default.
- W2086144613 hasAuthorship W2086144613A5008841181 @default.
- W2086144613 hasAuthorship W2086144613A5030356944 @default.
- W2086144613 hasAuthorship W2086144613A5030923663 @default.
- W2086144613 hasAuthorship W2086144613A5041081446 @default.
- W2086144613 hasAuthorship W2086144613A5086940680 @default.
- W2086144613 hasConcept C126322002 @default.
- W2086144613 hasConcept C134018914 @default.
- W2086144613 hasConcept C165220095 @default.
- W2086144613 hasConcept C181199279 @default.
- W2086144613 hasConcept C185592680 @default.
- W2086144613 hasConcept C24998067 @default.
- W2086144613 hasConcept C2777391703 @default.
- W2086144613 hasConcept C2779201268 @default.
- W2086144613 hasConcept C2779306644 @default.
- W2086144613 hasConcept C2779855799 @default.
- W2086144613 hasConcept C2781324293 @default.
- W2086144613 hasConcept C3018667095 @default.
- W2086144613 hasConcept C538909803 @default.
- W2086144613 hasConcept C55493867 @default.
- W2086144613 hasConcept C71924100 @default.
- W2086144613 hasConcept C86803240 @default.
- W2086144613 hasConceptScore W2086144613C126322002 @default.
- W2086144613 hasConceptScore W2086144613C134018914 @default.
- W2086144613 hasConceptScore W2086144613C165220095 @default.
- W2086144613 hasConceptScore W2086144613C181199279 @default.
- W2086144613 hasConceptScore W2086144613C185592680 @default.
- W2086144613 hasConceptScore W2086144613C24998067 @default.
- W2086144613 hasConceptScore W2086144613C2777391703 @default.
- W2086144613 hasConceptScore W2086144613C2779201268 @default.
- W2086144613 hasConceptScore W2086144613C2779306644 @default.
- W2086144613 hasConceptScore W2086144613C2779855799 @default.
- W2086144613 hasConceptScore W2086144613C2781324293 @default.
- W2086144613 hasConceptScore W2086144613C3018667095 @default.
- W2086144613 hasConceptScore W2086144613C538909803 @default.
- W2086144613 hasConceptScore W2086144613C55493867 @default.
- W2086144613 hasConceptScore W2086144613C71924100 @default.
- W2086144613 hasConceptScore W2086144613C86803240 @default.
- W2086144613 hasIssue "1" @default.
- W2086144613 hasLocation W20861446131 @default.
- W2086144613 hasLocation W20861446132 @default.
- W2086144613 hasOpenAccess W2086144613 @default.
- W2086144613 hasPrimaryLocation W20861446131 @default.
- W2086144613 hasRelatedWork W138803513 @default.
- W2086144613 hasRelatedWork W1986132654 @default.
- W2086144613 hasRelatedWork W2023901209 @default.
- W2086144613 hasRelatedWork W2045462791 @default.
- W2086144613 hasRelatedWork W2082140668 @default.
- W2086144613 hasRelatedWork W2127828366 @default.
- W2086144613 hasRelatedWork W2140792307 @default.
- W2086144613 hasRelatedWork W2151350502 @default.
- W2086144613 hasRelatedWork W222303599 @default.
- W2086144613 hasRelatedWork W2749044561 @default.
- W2086144613 hasVolume "392" @default.
- W2086144613 isParatext "false" @default.
- W2086144613 isRetracted "false" @default.
- W2086144613 magId "2086144613" @default.
- W2086144613 workType "article" @default.