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• W2086146474 startingPage "27" @default.
• W2086146474 abstract "The functional organization of the insular cortex was studied by recording neuronal responses to visceral sensory stimuli. Horseradish peroxidase (HRP) was then iontophoresed at the recording sites to identify afferents from the ventrobasal thalamus to specific visceroceptive sites in the insular cortex. The relationship of the ventrobasal thalamus to the insular cortex and to brainstem relay nuclei for the ascending visceral projections was then examined by using the axonal transport of HRP, wheat germ agglutinin conjugated to HRP (WGA-HRP), and fluorescent dyes. Of a total of 55 neurons that were tested for responses to visceral sensory stimuli, 33 units responded to atleast one visceral sensory modality: 6 received gastric mechanoreceptor input, 8 responded to taste inputs, 13 were activated by arterial chemoreceptors and/or showed respiratory related activity, and 6 responded to cardiovascular baroreceptor stimulation. On the basis of its cytoarchitecture and connections with the thalamus, the insular cortex was divided into a dorsal granular area, an intermediate dysgranular region, and a ventral agranular strip. Taste-responsive neurons were located anteriorly, primarily in the dysgranular region, whereas unit responses to general visceral modalities were distributed dorsally and posteriorly in the granular insular cortex. Gastric mechanoreceptor-responsive units were situated more dorsally and anteriorly in the granular insular cortex, while cardiopulmonary inputs were located more ventrally and posteriorly. Injections of HRP into the gustatory insular cortex resulted in retrograde labeling of neurons in the parvicellular part of the ventroposterior medial thalamic nucleus (VPMpc). Injections into the general visceral insular cortex retrogradely labeled neurons lateral to VPMpc in the ventroposterior lateral parvicellular thalamic nucleus (VPLpc). Injections of HRP, WGA-HRP, and fluorescent dyes into VPMpc and VPLpc verified that their projection to the insular cortex is topographically organized. In the same experiments, retrogradely labeled neurons in the parabrachial nucleus identified the likely subnuclei within this nucleus for relay of visceral sensory information to the thalamus. Injections of WGA-HRP into the parabrachial nucleus demonstrated that its projection to the ventrobasal thalamus is also topographically organized. These results demonstrate the relationship of general visceral and special visceral (taste) representations in the insular cortex. The ascending pathway for visceral sensory information appears to be viscerotopically organized at all levels of the neuraxis, including the insular cortex." @default.
• W2086146474 created "2016-06-24" @default.
• W2086146474 creator A5027042734 @default.
• W2086146474 creator A5059300906 @default.
• W2086146474 date "1987-08-01" @default.
• W2086146474 modified "2023-10-11" @default.
• W2086146474 title "Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat" @default.
• W2086146474 cites W1967534613 @default.
• W2086146474 cites W1970718804 @default.
• W2086146474 cites W1970758810 @default.
• W2086146474 cites W1976204462 @default.
• W2086146474 cites W1976876069 @default.
• W2086146474 cites W1983659005 @default.
• W2086146474 cites W1984145644 @default.
• W2086146474 cites W1985522462 @default.
• W2086146474 cites W1987448602 @default.
• W2086146474 cites W1988931656 @default.
• W2086146474 cites W1989396341 @default.
• W2086146474 cites W1997953694 @default.
• W2086146474 cites W1999641095 @default.
• W2086146474 cites W1999722313 @default.
• W2086146474 cites W2002746539 @default.
• W2086146474 cites W2005688316 @default.
• W2086146474 cites W2008303605 @default.
• W2086146474 cites W2008947929 @default.
• W2086146474 cites W2010115753 @default.
• W2086146474 cites W2011957206 @default.
• W2086146474 cites W2013183583 @default.
• W2086146474 cites W2015438958 @default.
• W2086146474 cites W2024689361 @default.
• W2086146474 cites W2029035945 @default.
• W2086146474 cites W2030916992 @default.
• W2086146474 cites W2032190662 @default.
• W2086146474 cites W2038547546 @default.
• W2086146474 cites W2041798363 @default.
• W2086146474 cites W2044249049 @default.
• W2086146474 cites W2044657054 @default.
• W2086146474 cites W2048859902 @default.
• W2086146474 cites W2050257074 @default.
• W2086146474 cites W2050280286 @default.
• W2086146474 cites W2050335665 @default.
• W2086146474 cites W2054281595 @default.
• W2086146474 cites W2054888366 @default.
• W2086146474 cites W2060042526 @default.
• W2086146474 cites W2062258113 @default.
• W2086146474 cites W2063633597 @default.
• W2086146474 cites W2065645858 @default.
• W2086146474 cites W2072071294 @default.
• W2086146474 cites W2072213364 @default.
• W2086146474 cites W2076821251 @default.
• W2086146474 cites W2078521408 @default.
• W2086146474 cites W2082142058 @default.
• W2086146474 cites W2084831872 @default.
• W2086146474 cites W2088262856 @default.
• W2086146474 cites W2108482232 @default.
• W2086146474 cites W2110401763 @default.
• W2086146474 cites W2123095717 @default.
• W2086146474 cites W2131784975 @default.
• W2086146474 cites W2134904201 @default.
• W2086146474 cites W2173243785 @default.
• W2086146474 cites W2188290152 @default.
• W2086146474 cites W2236303661 @default.
• W2086146474 cites W2270582807 @default.
• W2086146474 cites W2281043255 @default.
• W2086146474 cites W2317520538 @default.
• W2086146474 cites W2334299356 @default.
• W2086146474 cites W2345446293 @default.
• W2086146474 cites W2396569902 @default.
• W2086146474 cites W2396613622 @default.
• W2086146474 cites W2402470904 @default.
• W2086146474 cites W2406354681 @default.
• W2086146474 cites W2408529123 @default.
• W2086146474 cites W2411974024 @default.
• W2086146474 cites W2780382187 @default.
• W2086146474 cites W4235541760 @default.
• W2086146474 cites W4242632933 @default.
• W2086146474 cites W4250078418 @default.
• W2086146474 doi "https://doi.org/10.1002/cne.902620104" @default.
• W2086146474 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2442207" @default.
• W2086146474 hasPublicationYear "1987" @default.
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