Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086359073> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2086359073 endingPage "1366" @default.
- W2086359073 startingPage "1353" @default.
- W2086359073 abstract "Synthesis of 2-Substituted Imidazole Nucleosides Condensation of the trimethylsilyl derivatives of 2-substituted diethyl and dimethyl imidazole-4,5-dicarboxylates (3–5 and 7–9) with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (2) in the presence of trimethysilyl trifluoromethanesulfonate provided the 2-substituted diethyl and dimethyl 1-(2′,3′, 5′-tri-O-benzoyl-β-D-ribofuranosyl)imidazole-4, 5-dicarboxylates 10–15. These were treated with ammonia to afford the 2-substituted 1-(β-D-ribofuranosyl)imidazole-4,5-dicarboxamides 16–21. Treatment of 2-methyl-(16) and 2-ethyl-1-(β-D-ribofuranosyl)imidazole-4,5-dicarboxamide (17) with fuming nitric acid in oleum at −30° yielded the nitric acid esters 23 and 24. Besides the esterification of the sugar hydroxyl groups one H-atom of the imidazolecarboxamide function at C(5) in these nucleosides was also substituted by the NO2 group. The conformations in solution of 16 and 23 have been determined by 1H- and 13C-NMR. spectroscopy. These studies indicate that the nucleosides exist in dimethyl-sulfoxide solution preferentially in the S-gg-syn-conformation (16) and N-gt-conformation (23). In the crystal structure of nucleoside 23, the ribose was found to be in the O(1′)endo, C(1′)exo twist conformation. The conformation about C(4′), C(5′) is gauche-trans and the molecule exists in the syn form." @default.
- W2086359073 created "2016-06-24" @default.
- W2086359073 creator A5036906017 @default.
- W2086359073 creator A5049721284 @default.
- W2086359073 creator A5053175574 @default.
- W2086359073 date "1980-09-17" @default.
- W2086359073 modified "2023-10-06" @default.
- W2086359073 title "Synthese von Nucleosiden aus 2-substituierten Imidazolen" @default.
- W2086359073 cites W1515377228 @default.
- W2086359073 cites W1986943405 @default.
- W2086359073 cites W1999046009 @default.
- W2086359073 cites W2005727931 @default.
- W2086359073 cites W2009828525 @default.
- W2086359073 cites W2049842470 @default.
- W2086359073 cites W2050053784 @default.
- W2086359073 cites W2052772948 @default.
- W2086359073 cites W2054758978 @default.
- W2086359073 cites W2054954359 @default.
- W2086359073 cites W2056479069 @default.
- W2086359073 cites W2061822610 @default.
- W2086359073 cites W2070819831 @default.
- W2086359073 cites W2073134966 @default.
- W2086359073 cites W2084359121 @default.
- W2086359073 cites W2095299167 @default.
- W2086359073 cites W2135364038 @default.
- W2086359073 cites W2158214502 @default.
- W2086359073 doi "https://doi.org/10.1002/hlca.19800630602" @default.
- W2086359073 hasPublicationYear "1980" @default.
- W2086359073 type Work @default.
- W2086359073 sameAs 2086359073 @default.
- W2086359073 citedByCount "8" @default.
- W2086359073 countsByYear W20863590732013 @default.
- W2086359073 crossrefType "journal-article" @default.
- W2086359073 hasAuthorship W2086359073A5036906017 @default.
- W2086359073 hasAuthorship W2086359073A5049721284 @default.
- W2086359073 hasAuthorship W2086359073A5053175574 @default.
- W2086359073 hasConcept C155647269 @default.
- W2086359073 hasConcept C161790260 @default.
- W2086359073 hasConcept C178790620 @default.
- W2086359073 hasConcept C185592680 @default.
- W2086359073 hasConcept C21774173 @default.
- W2086359073 hasConcept C2776300020 @default.
- W2086359073 hasConcept C2779572362 @default.
- W2086359073 hasConcept C2780874372 @default.
- W2086359073 hasConcept C66974803 @default.
- W2086359073 hasConcept C71240020 @default.
- W2086359073 hasConceptScore W2086359073C155647269 @default.
- W2086359073 hasConceptScore W2086359073C161790260 @default.
- W2086359073 hasConceptScore W2086359073C178790620 @default.
- W2086359073 hasConceptScore W2086359073C185592680 @default.
- W2086359073 hasConceptScore W2086359073C21774173 @default.
- W2086359073 hasConceptScore W2086359073C2776300020 @default.
- W2086359073 hasConceptScore W2086359073C2779572362 @default.
- W2086359073 hasConceptScore W2086359073C2780874372 @default.
- W2086359073 hasConceptScore W2086359073C66974803 @default.
- W2086359073 hasConceptScore W2086359073C71240020 @default.
- W2086359073 hasIssue "6" @default.
- W2086359073 hasLocation W20863590731 @default.
- W2086359073 hasOpenAccess W2086359073 @default.
- W2086359073 hasPrimaryLocation W20863590731 @default.
- W2086359073 hasRelatedWork W1993274142 @default.
- W2086359073 hasRelatedWork W2016881336 @default.
- W2086359073 hasRelatedWork W2077942692 @default.
- W2086359073 hasRelatedWork W2080822529 @default.
- W2086359073 hasRelatedWork W2084893281 @default.
- W2086359073 hasRelatedWork W2090185271 @default.
- W2086359073 hasRelatedWork W2950122397 @default.
- W2086359073 hasRelatedWork W2950210240 @default.
- W2086359073 hasRelatedWork W2952508841 @default.
- W2086359073 hasRelatedWork W8043102 @default.
- W2086359073 hasVolume "63" @default.
- W2086359073 isParatext "false" @default.
- W2086359073 isRetracted "false" @default.
- W2086359073 magId "2086359073" @default.
- W2086359073 workType "article" @default.