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- W2086367457 abstract "Unidirectional and rotary shadowing techniques have been applied in studying the surface structure of two types of intermediate filaments. Keratin filaments and neurofilaments demonstrate a approximately 21-nm axial periodicity which probably indicates the helical pitch of the outer shell of the filament. Analysis of unidirectionally shadowed keratin showed that the helix is left-handed. The observation of a left-handed helix of 21-nm pitch supports the three-stranded protofilament model of Fraser, Macrae, and Suzuki (1976, J. Mol. Biol. 108:435-452), and indicates that keratin filaments probably consist of 10 three-stranded protofilaments surrounding a core of three such protofilaments, as predicted by models based on x-ray diffraction of hard keratin filaments. Neurofilaments do not demonstrate an easily identifiable hand, so their consistency with the model is, as yet, uncertain." @default.
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- W2086367457 date "1982-09-01" @default.
- W2086367457 modified "2023-10-13" @default.
- W2086367457 title "Visualization of a 21-nm axial periodicity in shadowed keratin filaments and neurofilaments." @default.
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- W2086367457 doi "https://doi.org/10.1083/jcb.94.3.592" @default.
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