Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086404611> ?p ?o ?g. }
- W2086404611 endingPage "507" @default.
- W2086404611 startingPage "485" @default.
- W2086404611 abstract "Accumulating evidence indicates that carbon nanotubes (CNTs) are biopersistent and can cause lung damage. With similar fibrous morphology and mode of exposure to asbestos, a known human carcinogen, growing concern has arisen for elevated risk of CNT-induced lung carcinogenesis; however, relatively little is known about the long-term carcinogenic effect of CNT. Neoplastic transformation is a key early event leading to carcinogenesis. We studied the ability of single- and multi-walled CNTs to induce neoplastic transformation of human lung epithelial cells compared to asbestos. Long-term (6-month) exposure of the cells to occupationally relevant concentrations of CNT in culture caused a neoplastic-like transformation phenotype as demonstrated by increased cell proliferation, anchorage-independent growth, invasion and angiogenesis. Whole-genome expression signature and protein expression analyses showed that single- and multi-walled CNTs shared similar signaling signatures which were distinct from asbestos. These results provide novel toxicogenomic information and suggest distinct particle-associated mechanisms of neoplasia promotion induced by CNTs and asbestos." @default.
- W2086404611 created "2016-06-24" @default.
- W2086404611 creator A5006031913 @default.
- W2086404611 creator A5019796793 @default.
- W2086404611 creator A5036894204 @default.
- W2086404611 creator A5047263911 @default.
- W2086404611 creator A5054459491 @default.
- W2086404611 creator A5056089597 @default.
- W2086404611 creator A5080894648 @default.
- W2086404611 date "2013-05-28" @default.
- W2086404611 modified "2023-10-10" @default.
- W2086404611 title "Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells" @default.
- W2086404611 cites W1516095885 @default.
- W2086404611 cites W1964237645 @default.
- W2086404611 cites W1964921458 @default.
- W2086404611 cites W1967249788 @default.
- W2086404611 cites W1975059364 @default.
- W2086404611 cites W1981013578 @default.
- W2086404611 cites W1984273678 @default.
- W2086404611 cites W1986166754 @default.
- W2086404611 cites W1994062800 @default.
- W2086404611 cites W1996292266 @default.
- W2086404611 cites W2001622142 @default.
- W2086404611 cites W2003116152 @default.
- W2086404611 cites W2008194851 @default.
- W2086404611 cites W2009004909 @default.
- W2086404611 cites W2009925138 @default.
- W2086404611 cites W2011021235 @default.
- W2086404611 cites W2011168240 @default.
- W2086404611 cites W2011707607 @default.
- W2086404611 cites W2011913041 @default.
- W2086404611 cites W2019720390 @default.
- W2086404611 cites W2019818029 @default.
- W2086404611 cites W2021149374 @default.
- W2086404611 cites W2034131665 @default.
- W2086404611 cites W2034343019 @default.
- W2086404611 cites W2039332722 @default.
- W2086404611 cites W2046315474 @default.
- W2086404611 cites W2050083788 @default.
- W2086404611 cites W2052947934 @default.
- W2086404611 cites W2055875511 @default.
- W2086404611 cites W2056309150 @default.
- W2086404611 cites W2058189357 @default.
- W2086404611 cites W2060355103 @default.
- W2086404611 cites W2064476069 @default.
- W2086404611 cites W2067207301 @default.
- W2086404611 cites W2070304486 @default.
- W2086404611 cites W2070619601 @default.
- W2086404611 cites W2071776935 @default.
- W2086404611 cites W2072131879 @default.
- W2086404611 cites W2082247621 @default.
- W2086404611 cites W2090700757 @default.
- W2086404611 cites W2092189141 @default.
- W2086404611 cites W2097693682 @default.
- W2086404611 cites W2099717039 @default.
- W2086404611 cites W2101011425 @default.
- W2086404611 cites W2101075149 @default.
- W2086404611 cites W2101183319 @default.
- W2086404611 cites W2102346500 @default.
- W2086404611 cites W2103614683 @default.
- W2086404611 cites W2112844455 @default.
- W2086404611 cites W2115450306 @default.
- W2086404611 cites W2115488868 @default.
- W2086404611 cites W2117692326 @default.
- W2086404611 cites W2118008112 @default.
- W2086404611 cites W2119538646 @default.
- W2086404611 cites W2123299551 @default.
- W2086404611 cites W2124250906 @default.
- W2086404611 cites W2128976939 @default.
- W2086404611 cites W2130406156 @default.
- W2086404611 cites W2131628918 @default.
- W2086404611 cites W2131969570 @default.
- W2086404611 cites W2133937363 @default.
- W2086404611 cites W2138003976 @default.
- W2086404611 cites W2140036981 @default.
- W2086404611 cites W2140897409 @default.
- W2086404611 cites W2144674981 @default.
- W2086404611 cites W2151609134 @default.
- W2086404611 cites W2153649717 @default.
- W2086404611 cites W2156827867 @default.
- W2086404611 cites W2160275284 @default.
- W2086404611 cites W2163798887 @default.
- W2086404611 cites W2165987864 @default.
- W2086404611 cites W2166278470 @default.
- W2086404611 cites W2171372912 @default.
- W2086404611 cites W2312549095 @default.
- W2086404611 doi "https://doi.org/10.3109/17435390.2013.801089" @default.
- W2086404611 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4599578" @default.
- W2086404611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23634900" @default.
- W2086404611 hasPublicationYear "2013" @default.
- W2086404611 type Work @default.
- W2086404611 sameAs 2086404611 @default.
- W2086404611 citedByCount "63" @default.
- W2086404611 countsByYear W20864046112013 @default.
- W2086404611 countsByYear W20864046112014 @default.
- W2086404611 countsByYear W20864046112015 @default.
- W2086404611 countsByYear W20864046112016 @default.
- W2086404611 countsByYear W20864046112017 @default.