FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086451680> ?p ?o ?g. }

• W2086451680 endingPage "497" @default.
• W2086451680 startingPage "488" @default.
• W2086451680 abstract "The purpose of the present study was to identify the association of the Pro12Ala polymorphism in the PPAR-γ2 gene with diabetes, insulinaemia and insulin resistance. A meta-analysis study was carried out based on studies conducted in the last 10 years, using the databases PubMed, ISI Web of Knowledge, High Wire Press and Scielo, and the reference lists of the obtained articles. We included original studies that showed the relationship between the Pro12Ala polymorphism in the PPAR-γ2 gene and type 2 diabetes mellitus (T2DM), insulinaemia and insulin resistance. Statistical analyses were conducted using the program RevMAn 5.0. The Mantel–Haenszel test was used to estimate the OR and the 95 % CI of the dichotomous variable, while the standardised effect size was used to estimate the average standardised mean difference and 95 % CI of continuous variables. The studies were subgrouped by ethnicity and overweight status. Forty-one studies were analysed, including a global sample of 30 612 subjects. We found a significant association of the Ala allele with the lowest risk of T2DM in Caucasians (OR 0·80; 95 % CI 0·65, 0·98), lower serum insulin (standardised effect size: − 0·05; 95 % CI − 0·09, − 0·00; P = 0·04), and greater sensitivity to insulin in overweight individuals (homeostasis model assessment of insulin resistance standardised effect size: − 0·07; 95 % CI − 0·13, − 0·01; P = 0·02). Considering that the Pro12Ala polymorphism in the PPAR-γ2 gene is one of the factors related to insulin sensitivity, the present study demonstrated a significant effect of the Ala allele on lower development of T2DM in Caucasians and greater sensitivity to insulin in overweight subjects." @default.
• W2086451680 created "2016-06-24" @default.
• W2086451680 creator A5026605991 @default.
• W2086451680 creator A5030977916 @default.
• W2086451680 date "2010-04-27" @default.
• W2086451680 modified "2023-09-23" @default.
• W2086451680 title "The Ala allele in the <i>PPAR-γ2</i> gene is associated with reduced risk of type 2 diabetes mellitus in Caucasians and improved insulin sensitivity in overweight subjects" @default.
• W2086451680 cites W1485161311 @default.
• W2086451680 cites W1527649416 @default.
• W2086451680 cites W1979892446 @default.
• W2086451680 cites W1980163360 @default.
• W2086451680 cites W1999898110 @default.
• W2086451680 cites W2003528418 @default.
• W2086451680 cites W2010785301 @default.
• W2086451680 cites W2016314884 @default.
• W2086451680 cites W2019405117 @default.
• W2086451680 cites W2028661874 @default.
• W2086451680 cites W2031633487 @default.
• W2086451680 cites W2032474323 @default.
• W2086451680 cites W2034932723 @default.
• W2086451680 cites W2036504695 @default.
• W2086451680 cites W2042694949 @default.
• W2086451680 cites W2047498347 @default.
• W2086451680 cites W2047687800 @default.
• W2086451680 cites W2054993322 @default.
• W2086451680 cites W2064012045 @default.
• W2086451680 cites W2075564716 @default.
• W2086451680 cites W2095543599 @default.
• W2086451680 cites W2095770480 @default.
• W2086451680 cites W2096491557 @default.
• W2086451680 cites W2098267166 @default.
• W2086451680 cites W2101796228 @default.
• W2086451680 cites W2101910056 @default.
• W2086451680 cites W2104855782 @default.
• W2086451680 cites W2111888395 @default.
• W2086451680 cites W2114825530 @default.
• W2086451680 cites W2115953242 @default.
• W2086451680 cites W2118387179 @default.
• W2086451680 cites W2125435699 @default.
• W2086451680 cites W2132634176 @default.
• W2086451680 cites W2134429084 @default.
• W2086451680 cites W2136143511 @default.
• W2086451680 cites W2136358718 @default.
• W2086451680 cites W2139292825 @default.
• W2086451680 cites W2139663495 @default.
• W2086451680 cites W2142995800 @default.
• W2086451680 cites W2148142390 @default.
• W2086451680 cites W2149524485 @default.
• W2086451680 cites W2160234571 @default.
• W2086451680 cites W2164743647 @default.
• W2086451680 cites W2171269660 @default.
• W2086451680 cites W4250028052 @default.
• W2086451680 doi "https://doi.org/10.1017/s0007114510000851" @default.
• W2086451680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20420754" @default.
• W2086451680 hasPublicationYear "2010" @default.
• W2086451680 type Work @default.
• W2086451680 sameAs 2086451680 @default.
• W2086451680 citedByCount "37" @default.
• W2086451680 countsByYear W20864516802012 @default.
• W2086451680 countsByYear W20864516802013 @default.
• W2086451680 countsByYear W20864516802014 @default.
• W2086451680 countsByYear W20864516802015 @default.
• W2086451680 countsByYear W20864516802016 @default.
• W2086451680 countsByYear W20864516802017 @default.
• W2086451680 countsByYear W20864516802018 @default.
• W2086451680 countsByYear W20864516802019 @default.
• W2086451680 countsByYear W20864516802020 @default.
• W2086451680 crossrefType "journal-article" @default.
• W2086451680 hasAuthorship W2086451680A5026605991 @default.
• W2086451680 hasAuthorship W2086451680A5030977916 @default.
• W2086451680 hasBestOaLocation W20864516801 @default.
• W2086451680 hasConcept C126322002 @default.
• W2086451680 hasConcept C134018914 @default.
• W2086451680 hasConcept C2777180221 @default.
• W2086451680 hasConcept C2777391703 @default.
• W2086451680 hasConcept C2779306644 @default.
• W2086451680 hasConcept C2780586474 @default.
• W2086451680 hasConcept C2910068830 @default.
• W2086451680 hasConcept C511355011 @default.
• W2086451680 hasConcept C555293320 @default.
• W2086451680 hasConcept C71924100 @default.
• W2086451680 hasConceptScore W2086451680C126322002 @default.
• W2086451680 hasConceptScore W2086451680C134018914 @default.
• W2086451680 hasConceptScore W2086451680C2777180221 @default.
• W2086451680 hasConceptScore W2086451680C2777391703 @default.
• W2086451680 hasConceptScore W2086451680C2779306644 @default.
• W2086451680 hasConceptScore W2086451680C2780586474 @default.
• W2086451680 hasConceptScore W2086451680C2910068830 @default.
• W2086451680 hasConceptScore W2086451680C511355011 @default.
• W2086451680 hasConceptScore W2086451680C555293320 @default.
• W2086451680 hasConceptScore W2086451680C71924100 @default.
• W2086451680 hasIssue "4" @default.
• W2086451680 hasLocation W20864516801 @default.
• W2086451680 hasLocation W20864516802 @default.
• W2086451680 hasOpenAccess W2086451680 @default.
• W2086451680 hasPrimaryLocation W20864516801 @default.
• W2086451680 hasRelatedWork W138803513 @default.
• W2086451680 hasRelatedWork W1979252938 @default.

• next