FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086553307> ?p ?o ?g. }

• W2086553307 endingPage "1345" @default.
• W2086553307 startingPage "1340" @default.
• W2086553307 abstract "Thyrotoxic (hypokalemic) periodic paralysis (TPP) is a frequent complication of thyrotoxicosis among Chinese men. To determine the genetic association of TPP, we studied 97 male TPP patients, 77 Graves’ disease patients without TPP, and 100 normal male subjects. Mutations of the voltage-dependent calcium channel (Cav1.1), sodium channel (Nav1.4), and potassium channel (Kv3.4), and association of the microsatellite markers on chromosome 1 in the region of the Na/K-ATPase subunits α1, α2, and β1 were studied. None of the TPP patients carried the known mutations in Cav1.1, Nav1.4, and Kv3.4 genes. There was no association of TPP with the microsatellite markers that mapped to 1p13, 1q21–23, and 1q22–25. We detected 12 single nucleotide polymorphisms (SNPs) in Cav1.1 in our population, of which three were novel. Significant differences in the SNP genotype distribution between TPP compared with Graves’ disease controls and normal controls were seen at the 5′ flanking region nucleotide (nt) −476 (P = 0.02), intron 2 nt 57 (P < 0.01), and intron 26 nt 67 (P < 0.001). Because these SNPs lie at or near the thyroid hormone responsive element, it is possible that they may affect the binding affinity of the thyroid hormone responsive element and modulate the stimulation of thyroid hormone on the Cav1.1 gene." @default.
• W2086553307 created "2016-06-24" @default.
• W2086553307 creator A5000319522 @default.
• W2086553307 creator A5047554081 @default.
• W2086553307 creator A5050198046 @default.
• W2086553307 creator A5067483174 @default.
• W2086553307 date "2004-03-01" @default.
• W2086553307 modified "2023-10-18" @default.
• W2086553307 title "Association of Novel Single Nucleotide Polymorphisms in the Calcium Channel α1 Subunit Gene (Ca_v1.1) and Thyrotoxic Periodic Paralysis" @default.
• W2086553307 cites W1556768294 @default.
• W2086553307 cites W1582683378 @default.
• W2086553307 cites W1886928378 @default.
• W2086553307 cites W1967101679 @default.
• W2086553307 cites W1968671979 @default.
• W2086553307 cites W1972430075 @default.
• W2086553307 cites W1976767166 @default.
• W2086553307 cites W1998130848 @default.
• W2086553307 cites W2000970297 @default.
• W2086553307 cites W2002058127 @default.
• W2086553307 cites W2010215247 @default.
• W2086553307 cites W2022853974 @default.
• W2086553307 cites W2035064638 @default.
• W2086553307 cites W2036976592 @default.
• W2086553307 cites W2039877630 @default.
• W2086553307 cites W2042531363 @default.
• W2086553307 cites W2067200379 @default.
• W2086553307 cites W2069886131 @default.
• W2086553307 cites W2073944083 @default.
• W2086553307 cites W2085669430 @default.
• W2086553307 cites W2088714432 @default.
• W2086553307 cites W2104689137 @default.
• W2086553307 cites W2113872117 @default.
• W2086553307 cites W2116708479 @default.
• W2086553307 cites W2130234511 @default.
• W2086553307 cites W2133203459 @default.
• W2086553307 cites W2139528954 @default.
• W2086553307 cites W2327690082 @default.
• W2086553307 cites W2397492738 @default.
• W2086553307 cites W2437464446 @default.
• W2086553307 cites W3147899325 @default.
• W2086553307 cites W774924855 @default.
• W2086553307 doi "https://doi.org/10.1210/jc.2003-030924" @default.
• W2086553307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15001631" @default.
• W2086553307 hasPublicationYear "2004" @default.
• W2086553307 type Work @default.
• W2086553307 sameAs 2086553307 @default.
• W2086553307 citedByCount "63" @default.
• W2086553307 countsByYear W20865533072012 @default.
• W2086553307 countsByYear W20865533072013 @default.
• W2086553307 countsByYear W20865533072014 @default.
• W2086553307 countsByYear W20865533072015 @default.
• W2086553307 countsByYear W20865533072016 @default.
• W2086553307 countsByYear W20865533072017 @default.
• W2086553307 countsByYear W20865533072018 @default.
• W2086553307 countsByYear W20865533072019 @default.
• W2086553307 countsByYear W20865533072020 @default.
• W2086553307 countsByYear W20865533072022 @default.
• W2086553307 countsByYear W20865533072023 @default.
• W2086553307 crossrefType "journal-article" @default.
• W2086553307 hasAuthorship W2086553307A5000319522 @default.
• W2086553307 hasAuthorship W2086553307A5047554081 @default.
• W2086553307 hasAuthorship W2086553307A5050198046 @default.
• W2086553307 hasAuthorship W2086553307A5067483174 @default.
• W2086553307 hasBestOaLocation W20865533071 @default.
• W2086553307 hasConcept C104317684 @default.
• W2086553307 hasConcept C126322002 @default.
• W2086553307 hasConcept C134018914 @default.
• W2086553307 hasConcept C135763542 @default.
• W2086553307 hasConcept C153209595 @default.
• W2086553307 hasConcept C2776652619 @default.
• W2086553307 hasConcept C2778242168 @default.
• W2086553307 hasConcept C2780955941 @default.
• W2086553307 hasConcept C2781079590 @default.
• W2086553307 hasConcept C526584372 @default.
• W2086553307 hasConcept C54355233 @default.
• W2086553307 hasConcept C71924100 @default.
• W2086553307 hasConcept C86803240 @default.
• W2086553307 hasConceptScore W2086553307C104317684 @default.
• W2086553307 hasConceptScore W2086553307C126322002 @default.
• W2086553307 hasConceptScore W2086553307C134018914 @default.
• W2086553307 hasConceptScore W2086553307C135763542 @default.
• W2086553307 hasConceptScore W2086553307C153209595 @default.
• W2086553307 hasConceptScore W2086553307C2776652619 @default.
• W2086553307 hasConceptScore W2086553307C2778242168 @default.
• W2086553307 hasConceptScore W2086553307C2780955941 @default.
• W2086553307 hasConceptScore W2086553307C2781079590 @default.
• W2086553307 hasConceptScore W2086553307C526584372 @default.
• W2086553307 hasConceptScore W2086553307C54355233 @default.
• W2086553307 hasConceptScore W2086553307C71924100 @default.
• W2086553307 hasConceptScore W2086553307C86803240 @default.
• W2086553307 hasIssue "3" @default.
• W2086553307 hasLocation W20865533071 @default.
• W2086553307 hasLocation W20865533072 @default.
• W2086553307 hasOpenAccess W2086553307 @default.
• W2086553307 hasPrimaryLocation W20865533071 @default.
• W2086553307 hasRelatedWork W1981968121 @default.
• W2086553307 hasRelatedWork W2010645160 @default.
• W2086553307 hasRelatedWork W2011960454 @default.

• next