Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086564153> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2086564153 endingPage "282" @default.
- W2086564153 startingPage "282" @default.
- W2086564153 abstract "Fenclonine (DL-parachlorophenylalanine), a potent inhibitor of serotonin synthesis, was administered to six patients with Huntington's chorea. Doses sufficient to reduce the cerebrospinal fluid (CSF) content of 5-hydroxyindoleacetic acid (5-HIAA), the principal catabolite of serotonin by nearly 50%, produced no consistent alteration in motor or behavioral function. The pretreatment concentration of 5-HIAA in CSF was in the normal range. Cerebrospinal fluid levels of homovanillic acid, a major catabolite of dopamine, did not change during drug treatment. The results thus fail to support the hypothesis that hyperfunction of serotonin-containing neural systems plays a crucial role in the pathogenesis of Huntington's disease." @default.
- W2086564153 created "2016-06-24" @default.
- W2086564153 creator A5002403864 @default.
- W2086564153 date "1972-03-01" @default.
- W2086564153 modified "2023-09-24" @default.
- W2086564153 title "Huntington's Chorea" @default.
- W2086564153 cites W1964008167 @default.
- W2086564153 cites W1971216003 @default.
- W2086564153 cites W1979949969 @default.
- W2086564153 cites W1989142203 @default.
- W2086564153 cites W1998799337 @default.
- W2086564153 cites W2015422990 @default.
- W2086564153 cites W2038911270 @default.
- W2086564153 cites W2046297063 @default.
- W2086564153 cites W2052396686 @default.
- W2086564153 cites W2062442298 @default.
- W2086564153 cites W2078807780 @default.
- W2086564153 cites W2078978843 @default.
- W2086564153 cites W2149330955 @default.
- W2086564153 cites W2299861533 @default.
- W2086564153 cites W2327478793 @default.
- W2086564153 cites W2337339762 @default.
- W2086564153 cites W2435658464 @default.
- W2086564153 cites W2466346142 @default.
- W2086564153 cites W2474738334 @default.
- W2086564153 doi "https://doi.org/10.1001/archneur.1972.00490090108012" @default.
- W2086564153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4258630" @default.
- W2086564153 hasPublicationYear "1972" @default.
- W2086564153 type Work @default.
- W2086564153 sameAs 2086564153 @default.
- W2086564153 citedByCount "19" @default.
- W2086564153 countsByYear W20865641532017 @default.
- W2086564153 crossrefType "journal-article" @default.
- W2086564153 hasAuthorship W2086564153A5002403864 @default.
- W2086564153 hasConcept C126322002 @default.
- W2086564153 hasConcept C15744967 @default.
- W2086564153 hasConcept C169760540 @default.
- W2086564153 hasConcept C2778868616 @default.
- W2086564153 hasConcept C2779134260 @default.
- W2086564153 hasConcept C2780647506 @default.
- W2086564153 hasConcept C71924100 @default.
- W2086564153 hasConceptScore W2086564153C126322002 @default.
- W2086564153 hasConceptScore W2086564153C15744967 @default.
- W2086564153 hasConceptScore W2086564153C169760540 @default.
- W2086564153 hasConceptScore W2086564153C2778868616 @default.
- W2086564153 hasConceptScore W2086564153C2779134260 @default.
- W2086564153 hasConceptScore W2086564153C2780647506 @default.
- W2086564153 hasConceptScore W2086564153C71924100 @default.
- W2086564153 hasIssue "3" @default.
- W2086564153 hasLocation W20865641531 @default.
- W2086564153 hasLocation W20865641532 @default.
- W2086564153 hasOpenAccess W2086564153 @default.
- W2086564153 hasPrimaryLocation W20865641531 @default.
- W2086564153 hasRelatedWork W1997648025 @default.
- W2086564153 hasRelatedWork W2125652894 @default.
- W2086564153 hasRelatedWork W2150414946 @default.
- W2086564153 hasRelatedWork W2748952813 @default.
- W2086564153 hasRelatedWork W2773353270 @default.
- W2086564153 hasRelatedWork W2899084033 @default.
- W2086564153 hasRelatedWork W2917569963 @default.
- W2086564153 hasRelatedWork W3215349630 @default.
- W2086564153 hasRelatedWork W4244492395 @default.
- W2086564153 hasRelatedWork W4378619940 @default.
- W2086564153 hasVolume "26" @default.
- W2086564153 isParatext "false" @default.
- W2086564153 isRetracted "false" @default.
- W2086564153 magId "2086564153" @default.
- W2086564153 workType "article" @default.