FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086604377> ?p ?o ?g. }

• W2086604377 endingPage "1903" @default.
• W2086604377 startingPage "1886" @default.
• W2086604377 abstract "The lipid hypothesis of coronary heart disease proposes that a high total cholesterol level has a causative role in coronary heart disease (CHD), specifically in the development of atherosclerosis. It forms the basis for formulating target levels of serum cholesterol and hence the widespread use of statins for lowering cholesterol. An extension of the lipid hypothesis is the diet/heart hypothesis of coronary heart disease. This theory combines two ideas—that saturated fat raises cholesterol levels, and that a reduced saturated fat intake will lower cholesterol levels, thereby inhibiting the development of atherosclerosis and manifestations of CHD. Those who make diet recommendations or prescribe medication to reduce cholesterol may be unaware of the underpinning science. The original research behind these recommendations has given us “healthy heart” guidelines and preventive measures we assume to be true. While the lipid and diet/heart hypotheses are often presented as fact, they remain inadequately proven theories that have little agreement from experts. Historical perspectives can help us understand the basis of current-day beliefs. In the lipid hypothesis case, research from the 1950s and 60s was instrumental in its formation. This early work should not be considered irrelevant, outdated or obsolete because current recommendations from national heart associations in many countries continue to be shaped by these studies. This paper examines evidence used to formulate the lipid hypothesis and, subsequently, the diet/ heart hypothesis. By critically evaluating steps in the formation of the theory, inconsistencies, mistakes and alternate explanations become apparent and cast doubt on its validity." @default.
• W2086604377 created "2016-06-24" @default.
• W2086604377 creator A5046312873 @default.
• W2086604377 date "2014-01-01" @default.
• W2086604377 modified "2023-10-01" @default.
• W2086604377 title "Flaws, Fallacies and Facts: Reviewing the Early History of the Lipid and Diet/Heart Hypotheses" @default.
• W2086604377 cites W110180750 @default.
• W2086604377 cites W1492363377 @default.
• W2086604377 cites W1516932593 @default.
• W2086604377 cites W1534126065 @default.
• W2086604377 cites W1562430392 @default.
• W2086604377 cites W1568311619 @default.
• W2086604377 cites W1804920124 @default.
• W2086604377 cites W1877832778 @default.
• W2086604377 cites W1878413628 @default.
• W2086604377 cites W1883417440 @default.
• W2086604377 cites W1940807082 @default.
• W2086604377 cites W1965159232 @default.
• W2086604377 cites W1971224517 @default.
• W2086604377 cites W1974279484 @default.
• W2086604377 cites W1975845872 @default.
• W2086604377 cites W1981601639 @default.
• W2086604377 cites W1995366155 @default.
• W2086604377 cites W2000612011 @default.
• W2086604377 cites W2003003835 @default.
• W2086604377 cites W2003865501 @default.
• W2086604377 cites W2014504970 @default.
• W2086604377 cites W2019616743 @default.
• W2086604377 cites W2019643421 @default.
• W2086604377 cites W2020331440 @default.
• W2086604377 cites W2022050717 @default.
• W2086604377 cites W2024119019 @default.
• W2086604377 cites W2027832704 @default.
• W2086604377 cites W2029133236 @default.
• W2086604377 cites W2032378624 @default.
• W2086604377 cites W2036984943 @default.
• W2086604377 cites W2050319205 @default.
• W2086604377 cites W2059157516 @default.
• W2086604377 cites W2063738226 @default.
• W2086604377 cites W2065129742 @default.
• W2086604377 cites W2065596354 @default.
• W2086604377 cites W2066336721 @default.
• W2086604377 cites W2067407807 @default.
• W2086604377 cites W2071328111 @default.
• W2086604377 cites W2072548235 @default.
• W2086604377 cites W2075826151 @default.
• W2086604377 cites W2081580931 @default.
• W2086604377 cites W2083943389 @default.
• W2086604377 cites W2084978834 @default.
• W2086604377 cites W2087374284 @default.
• W2086604377 cites W2089655626 @default.
• W2086604377 cites W2122034743 @default.
• W2086604377 cites W2122248120 @default.
• W2086604377 cites W2131272908 @default.
• W2086604377 cites W2142549602 @default.
• W2086604377 cites W2149256287 @default.
• W2086604377 cites W2149800797 @default.
• W2086604377 cites W2155564116 @default.
• W2086604377 cites W2163853417 @default.
• W2086604377 cites W2164850907 @default.
• W2086604377 cites W2201088889 @default.
• W2086604377 cites W2201579395 @default.
• W2086604377 cites W2267958864 @default.
• W2086604377 cites W2299935524 @default.
• W2086604377 cites W2304537428 @default.
• W2086604377 cites W2313427715 @default.
• W2086604377 cites W2336495619 @default.
• W2086604377 cites W2399651649 @default.
• W2086604377 cites W2410748549 @default.
• W2086604377 cites W2410979608 @default.
• W2086604377 cites W2412219049 @default.
• W2086604377 cites W2416603699 @default.
• W2086604377 cites W2417569271 @default.
• W2086604377 cites W2436189501 @default.
• W2086604377 cites W2437929205 @default.
• W2086604377 cites W2464147281 @default.
• W2086604377 cites W2466169901 @default.
• W2086604377 cites W2580858241 @default.
• W2086604377 cites W2746328938 @default.
• W2086604377 cites W2807367275 @default.
• W2086604377 cites W3146861621 @default.
• W2086604377 cites W48546432 @default.
• W2086604377 cites W2181874231 @default.
• W2086604377 doi "https://doi.org/10.4236/fns.2014.519201" @default.
• W2086604377 hasPublicationYear "2014" @default.
• W2086604377 type Work @default.
• W2086604377 sameAs 2086604377 @default.
• W2086604377 citedByCount "2" @default.
• W2086604377 countsByYear W20866043772016 @default.
• W2086604377 countsByYear W20866043772020 @default.
• W2086604377 crossrefType "journal-article" @default.
• W2086604377 hasAuthorship W2086604377A5046312873 @default.
• W2086604377 hasBestOaLocation W20866043771 @default.
• W2086604377 hasConcept C126322002 @default.
• W2086604377 hasConcept C15744967 @default.
• W2086604377 hasConcept C2778163477 @default.
• W2086604377 hasConcept C2780074459 @default.
• W2086604377 hasConcept C3018906752 @default.

• next