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- W2086710909 abstract "Quaternization of (S)-α-bromophenylacetic acid amide (8) with hexamethylentetramine (hexamine) preceded with ca. 80% inversion of configuration. Accordingly, starting from the trimethylsilylester of N-(S)-(α-bromo-α-phenylacetyl)-6-aminopenicillanic acid (4) quaternization with hexamine and subsequent hydrolysis afforded N-(R)-α-phenylglycyl-6-aminopenicillanic acid (1, ampicillin). Some other model reactions have been investigated." @default.
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- W2086710909 date "1976-06-01" @default.
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- W2086710909 title "A new synthesis of ampicillin and related investigations" @default.
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- W2086710909 doi "https://doi.org/10.1002/jhet.5570130327" @default.
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