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- W2086726504 abstract "Pathogenic microbes often modulate phytohormone physiology in the host to their advantage. We previously showed that the Pseudomonas syringae effector protein AvrB perturbs hormone signaling, as exemplified by upregulated expression of jasmonic acid response genes, and enhances plant susceptibility. Here we show that these effects of AvrB require the Arabidopsis mitogen-activated protein kinase MAP kinase 4 (MPK4), HSP90 chaperone components, and the AvrB-interacting protein, RIN4. AvrB interacts with MPK4 and the HSP90 chaperone, and AvrB induces MPK4 activation in a manner promoted by HSP90; RIN4 likely acts downstream of MPK4. These findings link Arabidopsis proteins MPK4, HSP90, and RIN4 into a pathway that P. syringae AvrB activates for the benefit of the bacterium, perturbing hormone signaling and enhancing plant susceptibility." @default.
- W2086726504 created "2016-06-24" @default.
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- W2086726504 date "2010-02-01" @default.
- W2086726504 modified "2023-10-16" @default.
- W2086726504 title "Pseudomonas syringae Effector Protein AvrB Perturbs Arabidopsis Hormone Signaling by Activating MAP Kinase 4" @default.
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- W2086726504 doi "https://doi.org/10.1016/j.chom.2010.01.009" @default.
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