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• W2086746939 abstract "<b>Context:</b> Cirrhosis of liver is an important cause of morbidity and mortality and if associated with peripheral neuropathy (PN) it also poses a huge financial, psychological burden for the patients and their families. <b>Aim:</b> The aim of the present study was to study the magnitude of PN among subjects with cirrhosis of liver presenting to tertiary care teaching hospital in central rural India. <b>Settings and Design:</b> A cross-sectional study was performed in a tertiary care teaching hospital. <b>Materials and Methods:</b> In all patients of cirrhosis of liver irrespective of etiology, aged 15 and above, undergone clinical assessment for peripheral nervous systems damage and confirmed by nerve conduction studies. <b>Statistical Analysis Used:</b> We used chi square test to study associations. P value ≤0.05 was considered as significant. Crude odds ratios were computed to assess the strength of association between independent variables and dependent variables along with their 95% confidence intervals. <b>Results:</b> We included 207 of cirrhosis of liver patients admitted in medicine department from November 2010 through November 2013. Nearly 83% patients were male and 63.2% patients were under the age of 45 years. Common features in these patients were ascites (71%) splenomegaly (63.3%) pedal edema (61.4%) icterus (46.4%) tingling (44.9%) gastrointestinal bleeding(39.1%), ataxia (26.6%),numbness(26.6%),distal motor weakness (21.7%) and paresthesia(20.8%).Among the manifestation of peripheral nerve involvement, loss of ankle reflex was the most common feature in 51.7%, followed by loss of temperature sense 29.5%, loss of vibration sense 20.8%, loss of touch 16.4%, loss of position sense 14.5% and loss of pain in 6.3% of the patients. Peripheral neuropathy was found in 53.6% [95% CI: 46.58- 60.56] study subjects on electrophysiological study. <b>Conclusions:</b> Analysis of electrophysiological study shows that the PN is very common in study subjects with cirrhosis of liver, especially in male subjects, during the middle age group." @default.
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• W2086746939 date "2014-01-01" @default.
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• W2086746939 title "Magnitude of peripheral neuropathy in cirrhosis of liver patients from central rural India" @default.
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• W2086746939 doi "https://doi.org/10.4103/0972-2327.144012" @default.
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