Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086751043> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2086751043 endingPage "904" @default.
- W2086751043 startingPage "897" @default.
- W2086751043 abstract "Despite traditional therapy of a diuretic, angiotensin converting enzyme inhibitor, digoxin, or a combination of these drugs, survival of dogs with dilated cardiomyopathy (DCM) is low. Pimobendan, an inodilator, has both inotropic and balanced peripheral vasodilatory properties.Pimobendan when added to conventional therapy will improve morbidity and reduce case fatality rate in Doberman Pinschers with congestive heart failure (CHF) caused by DCM.Sixteen Doberman Pinschers in CHF caused by DCM.A prospective randomized, double-blind, placebo-controlled study with treatment failure as the primary and quality of life (QoL) indices as secondary outcome variables. Therapy consisted of furosemide (per os [PO] as required) and benazepril hydrochloride (0.5 mg/kg PO q12h) and dogs were randomized in pairs and by sex to receive pimobendan (0.25 mg/kg PO q12h) or placebo (1 tablet PO q12h).Pimobendan-treated dogs had a significant improvement in time to treatment failure (pimobendan median, 130.5 days; placebo median, 14 days; P= .002; risk ratio = 0.35, P= .003, lower 5% confidence limit = 0.13, upper 95% confidence limit = 0.71). Number and rate of dogs reaching treatment failure in the placebo group precluded the analysis of QoL.Pimobendan should be used as a first-line therapeutic in Doberman Pinschers for the treatment of CHF caused by DCM." @default.
- W2086751043 created "2016-06-24" @default.
- W2086751043 creator A5004445668 @default.
- W2086751043 creator A5040153609 @default.
- W2086751043 creator A5068605240 @default.
- W2086751043 creator A5074012625 @default.
- W2086751043 date "2008-07-01" @default.
- W2086751043 modified "2023-10-18" @default.
- W2086751043 title "Effect of Pimobendan on Case Fatality Rate in Doberman Pinschers with Congestive Heart Failure Caused by Dilated Cardiomyopathy" @default.
- W2086751043 cites W1969400014 @default.
- W2086751043 cites W1975254142 @default.
- W2086751043 cites W1982449560 @default.
- W2086751043 cites W2037194737 @default.
- W2086751043 cites W2042795952 @default.
- W2086751043 cites W2083073839 @default.
- W2086751043 cites W2092210865 @default.
- W2086751043 cites W2120798774 @default.
- W2086751043 cites W2166801127 @default.
- W2086751043 cites W2252796750 @default.
- W2086751043 cites W2288608339 @default.
- W2086751043 cites W2319534362 @default.
- W2086751043 cites W4230300754 @default.
- W2086751043 cites W4244085534 @default.
- W2086751043 doi "https://doi.org/10.1111/j.1939-1676.2008.0116.x" @default.
- W2086751043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18537880" @default.
- W2086751043 hasPublicationYear "2008" @default.
- W2086751043 type Work @default.
- W2086751043 sameAs 2086751043 @default.
- W2086751043 citedByCount "82" @default.
- W2086751043 countsByYear W20867510432012 @default.
- W2086751043 countsByYear W20867510432013 @default.
- W2086751043 countsByYear W20867510432014 @default.
- W2086751043 countsByYear W20867510432015 @default.
- W2086751043 countsByYear W20867510432016 @default.
- W2086751043 countsByYear W20867510432017 @default.
- W2086751043 countsByYear W20867510432018 @default.
- W2086751043 countsByYear W20867510432019 @default.
- W2086751043 countsByYear W20867510432020 @default.
- W2086751043 countsByYear W20867510432021 @default.
- W2086751043 countsByYear W20867510432022 @default.
- W2086751043 countsByYear W20867510432023 @default.
- W2086751043 crossrefType "journal-article" @default.
- W2086751043 hasAuthorship W2086751043A5004445668 @default.
- W2086751043 hasAuthorship W2086751043A5040153609 @default.
- W2086751043 hasAuthorship W2086751043A5068605240 @default.
- W2086751043 hasAuthorship W2086751043A5074012625 @default.
- W2086751043 hasConcept C126322002 @default.
- W2086751043 hasConcept C142724271 @default.
- W2086751043 hasConcept C164705383 @default.
- W2086751043 hasConcept C197934379 @default.
- W2086751043 hasConcept C204787440 @default.
- W2086751043 hasConcept C27081682 @default.
- W2086751043 hasConcept C2776383484 @default.
- W2086751043 hasConcept C2777482430 @default.
- W2086751043 hasConcept C2777955127 @default.
- W2086751043 hasConcept C2778198053 @default.
- W2086751043 hasConcept C71924100 @default.
- W2086751043 hasConcept C78085059 @default.
- W2086751043 hasConceptScore W2086751043C126322002 @default.
- W2086751043 hasConceptScore W2086751043C142724271 @default.
- W2086751043 hasConceptScore W2086751043C164705383 @default.
- W2086751043 hasConceptScore W2086751043C197934379 @default.
- W2086751043 hasConceptScore W2086751043C204787440 @default.
- W2086751043 hasConceptScore W2086751043C27081682 @default.
- W2086751043 hasConceptScore W2086751043C2776383484 @default.
- W2086751043 hasConceptScore W2086751043C2777482430 @default.
- W2086751043 hasConceptScore W2086751043C2777955127 @default.
- W2086751043 hasConceptScore W2086751043C2778198053 @default.
- W2086751043 hasConceptScore W2086751043C71924100 @default.
- W2086751043 hasConceptScore W2086751043C78085059 @default.
- W2086751043 hasIssue "4" @default.
- W2086751043 hasLocation W20867510431 @default.
- W2086751043 hasLocation W20867510432 @default.
- W2086751043 hasOpenAccess W2086751043 @default.
- W2086751043 hasPrimaryLocation W20867510431 @default.
- W2086751043 hasRelatedWork W1932289911 @default.
- W2086751043 hasRelatedWork W2000835410 @default.
- W2086751043 hasRelatedWork W2157742916 @default.
- W2086751043 hasRelatedWork W2399149996 @default.
- W2086751043 hasRelatedWork W2409515031 @default.
- W2086751043 hasRelatedWork W2412039507 @default.
- W2086751043 hasRelatedWork W2424026049 @default.
- W2086751043 hasRelatedWork W2909861902 @default.
- W2086751043 hasRelatedWork W3007328396 @default.
- W2086751043 hasRelatedWork W2188536347 @default.
- W2086751043 hasVolume "22" @default.
- W2086751043 isParatext "false" @default.
- W2086751043 isRetracted "false" @default.
- W2086751043 magId "2086751043" @default.
- W2086751043 workType "article" @default.