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- W2086751308 abstract "1-Octanol (an 8-C alcohol currently used as a food-flavoring agent) is known to inhibit tremor in essential tremor (ET) animal models at a much lower dose than ethyl alcohol. The authors conducted a randomized, placebo-controlled pilot trial of a single oral dose of 1 mg/kg of 1-octanol in 12 patients with ET. No significant side effects or signs of intoxication were observed. 1-Octanol significantly decreased tremor amplitude for up to 90 minutes. The results suggest 1-octanol as a well-tolerated and safe potential treatment for ET. Further trials are warranted." @default.
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- W2086751308 date "2004-01-12" @default.
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- W2086751308 title "Pilot trial of 1-octanol in essential tremor" @default.
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- W2086751308 doi "https://doi.org/10.1212/01.wnl.0000101722.95137.19" @default.
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