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• W2086784306 endingPage "215" @default.
• W2086784306 startingPage "202" @default.
• W2086784306 abstract "Infection with human immunodeficiency virus-1 (HIV-1) often leads to HIV-associated neurocognitive disorders (HAND) prior to the progression to acquired immunodeficiency syndrome (AIDS). At the cellular level, mitogen-activated protein kinases (MAPK) provide a family of signal transducers that regulate many processes in response to extracellular stimuli and environmental stress, such as viral infection. Recently, evidence has accumulated suggesting that p38 MAPK plays crucial roles in various pathological processes associated with HIV infection, ranging from macrophage activation to neurotoxicity and impairment of neurogenesis to lymphocyte apoptosis. Thus, p38 MAPK, which has generally been linked to stress-related signal transduction, may be an important mediator in the development of AIDS and HAND." @default.
• W2086784306 created "2016-06-24" @default.
• W2086784306 creator A5007785978 @default.
• W2086784306 creator A5072837198 @default.
• W2086784306 date "2011-02-01" @default.
• W2086784306 modified "2023-10-16" @default.
• W2086784306 title "Mitogen-Activated Protein Kinase p38 in HIV Infection and Associated Brain Injury" @default.
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