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- W2086784555 abstract "Sir, We report two Japanese patients with novel cutaneous manifestations that arose after receiving nutritional intravenous infusions for anorexia nervosa. Patients 1 and 2 were women aged 19 and 24 years, respectively. The former had been suffering from anorexia nervosa since August 1998; the latter since 1995, accompanied by systemic lupus erythematosus. Several days after starting a 1700‐kcal diet and 1000 mL peripheral intravenous infusion in patient 1, and intravenous hyperalimentation in patient 2, they developed skin lesions. Examination revealed dryness, severe oedema and numerous linear, reddish or brownish erythematous areas, 2–8 mm in width, on their legs and/or feet with severe pain (Fig. 1). Both had additional non‐dermatological symptoms including amenorrhoea, hypothermia, bradycardia, hypotension and muscle weakness. Laboratory data showed decreased white blood cell counts, hypoproteinaemia, hypoalbuminaemia, hypotriglyceridaemia, low blood sugar, low triiodothyronine, low insulin‐like growth factor‐1 and anaemia. Their weight was about 50% of their ideal, with severe anorexia nervosa. We stopped the infusion of patient 1; the intravenous hyperalimentation of patient 2 had already been discontinued because of a bacterial infection at the site of needle insertion. We gave them 20% albumin and furosemide and treated them with heparinoid and/or Azunol® ointment (0·033% 1,4‐dimethyl‐7‐isopropylazulene, an anti‐inflammatory agent) topically. As the oedema decreased, their lesions improved with only residual hyperpigmentation but no scarring or atrophy after 1 month." @default.
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- W2086784555 date "2001-08-01" @default.
- W2086784555 modified "2023-09-27" @default.
- W2086784555 title "Linear erythema craquele due to acute oedema in anorexia nervosa." @default.
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- W2086784555 doi "https://doi.org/10.1046/j.1365-2133.2001.04358.x" @default.
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