Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086791354> ?p ?o ?g. }
- W2086791354 endingPage "105" @default.
- W2086791354 startingPage "96" @default.
- W2086791354 abstract "Spinal cord hemisection at C2 (C2HS) severs bulbospinal inputs to ipsilateral phrenic motoneurons causing transient hemidiaphragm paralysis. The spontaneous crossed-phrenic phenomenon (sCPP) describes the spontaneous recovery of ipsilateral phrenic bursting following C2HS. We reasoned that the immediate (next breath) changes in tidal volume (V T ) induced by ipsilateral phrenicotomy during spontaneous breathing would provide a quantitative measure of the contribution of the sCPP to postinjury V T . Using this approach, we tested the hypothesis that the sCPP makes more substantial contributions to V T when respiratory drive is increased. Pneumotachography was used to measure V T in anesthetized, spontaneously breathing adult male rats at intervals following C2HS. A progressive increase in V T (ml/breath) occurred over an 8 wk period following C2HS during both poikilocapnic baseline breathing and hypercapnic respiratory challenge (7% inspired CO 2 ). The sCPP did not impact baseline breathing at 1–3 days postinjury since V T was unchanged after ipsilateral phrenicotomy. However, by 2 wk post-C2HS, baseline phrenicotomy caused a 16 ± 2% decline in V T ; a comparable 16 ± 4% decline occurred at 8 wk. Contrary to our hypothesis, the phrenicotomy-induced declines in V T (%) during hypercapnic respiratory stimulation did not differ from the baseline response at any postinjury time point (all P > 0.11). We conclude that by 2 wk post-C2HS the sCPP makes a meaningful contribution to V T that is similar across different levels of respiratory drive." @default.
- W2086791354 created "2016-06-24" @default.
- W2086791354 creator A5004750961 @default.
- W2086791354 creator A5011201539 @default.
- W2086791354 creator A5026177743 @default.
- W2086791354 creator A5038319158 @default.
- W2086791354 creator A5078454883 @default.
- W2086791354 date "2012-01-01" @default.
- W2086791354 modified "2023-09-27" @default.
- W2086791354 title "Contribution of the spontaneous crossed-phrenic phenomenon to inspiratory tidal volume in spontaneously breathing rats" @default.
- W2086791354 cites W1491908576 @default.
- W2086791354 cites W1524764210 @default.
- W2086791354 cites W1903050514 @default.
- W2086791354 cites W1961081041 @default.
- W2086791354 cites W1964478994 @default.
- W2086791354 cites W1965540540 @default.
- W2086791354 cites W1967013106 @default.
- W2086791354 cites W1967803715 @default.
- W2086791354 cites W1969312570 @default.
- W2086791354 cites W1976230683 @default.
- W2086791354 cites W1977982910 @default.
- W2086791354 cites W1978498062 @default.
- W2086791354 cites W1979922994 @default.
- W2086791354 cites W1981292036 @default.
- W2086791354 cites W1981461030 @default.
- W2086791354 cites W1982480010 @default.
- W2086791354 cites W1988952750 @default.
- W2086791354 cites W1989560803 @default.
- W2086791354 cites W1992547264 @default.
- W2086791354 cites W2011030862 @default.
- W2086791354 cites W2011259179 @default.
- W2086791354 cites W2015292698 @default.
- W2086791354 cites W2018899405 @default.
- W2086791354 cites W2022396588 @default.
- W2086791354 cites W2025477997 @default.
- W2086791354 cites W2051742717 @default.
- W2086791354 cites W2053630180 @default.
- W2086791354 cites W2064108055 @default.
- W2086791354 cites W2076687893 @default.
- W2086791354 cites W2076828182 @default.
- W2086791354 cites W2083248454 @default.
- W2086791354 cites W2091298636 @default.
- W2086791354 cites W2094145315 @default.
- W2086791354 cites W2109169983 @default.
- W2086791354 cites W2115978592 @default.
- W2086791354 cites W2125773804 @default.
- W2086791354 cites W2135557712 @default.
- W2086791354 cites W2145172578 @default.
- W2086791354 cites W2159019217 @default.
- W2086791354 cites W2161385489 @default.
- W2086791354 cites W2171962458 @default.
- W2086791354 cites W2174138353 @default.
- W2086791354 cites W2255814883 @default.
- W2086791354 cites W2272744191 @default.
- W2086791354 cites W2272933370 @default.
- W2086791354 cites W2328454973 @default.
- W2086791354 cites W90815164 @default.
- W2086791354 doi "https://doi.org/10.1152/japplphysiol.00690.2011" @default.
- W2086791354 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3290423" @default.
- W2086791354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22033536" @default.
- W2086791354 hasPublicationYear "2012" @default.
- W2086791354 type Work @default.
- W2086791354 sameAs 2086791354 @default.
- W2086791354 citedByCount "35" @default.
- W2086791354 countsByYear W20867913542012 @default.
- W2086791354 countsByYear W20867913542013 @default.
- W2086791354 countsByYear W20867913542014 @default.
- W2086791354 countsByYear W20867913542015 @default.
- W2086791354 countsByYear W20867913542016 @default.
- W2086791354 countsByYear W20867913542017 @default.
- W2086791354 countsByYear W20867913542018 @default.
- W2086791354 countsByYear W20867913542019 @default.
- W2086791354 countsByYear W20867913542020 @default.
- W2086791354 countsByYear W20867913542021 @default.
- W2086791354 countsByYear W20867913542022 @default.
- W2086791354 countsByYear W20867913542023 @default.
- W2086791354 crossrefType "journal-article" @default.
- W2086791354 hasAuthorship W2086791354A5004750961 @default.
- W2086791354 hasAuthorship W2086791354A5011201539 @default.
- W2086791354 hasAuthorship W2086791354A5026177743 @default.
- W2086791354 hasAuthorship W2086791354A5038319158 @default.
- W2086791354 hasAuthorship W2086791354A5078454883 @default.
- W2086791354 hasBestOaLocation W20867913542 @default.
- W2086791354 hasConcept C105702510 @default.
- W2086791354 hasConcept C118552586 @default.
- W2086791354 hasConcept C127413603 @default.
- W2086791354 hasConcept C200457457 @default.
- W2086791354 hasConcept C2777099253 @default.
- W2086791354 hasConcept C2777257755 @default.
- W2086791354 hasConcept C2780775167 @default.
- W2086791354 hasConcept C39300077 @default.
- W2086791354 hasConcept C42219234 @default.
- W2086791354 hasConcept C534529494 @default.
- W2086791354 hasConcept C71924100 @default.
- W2086791354 hasConcept C78519656 @default.
- W2086791354 hasConceptScore W2086791354C105702510 @default.
- W2086791354 hasConceptScore W2086791354C118552586 @default.
- W2086791354 hasConceptScore W2086791354C127413603 @default.