Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086793918> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2086793918 endingPage "145" @default.
- W2086793918 startingPage "139" @default.
- W2086793918 abstract "Guaiacol, which is a phenolic compound with a methoxy group and used in traditional dental pulp sedation, has the property of inducing cell proliferation. To clarify these mechanisms of guaiacol, this study examined the hydroxyl radical (*OH) scavenging effects of guaiacol in vitro. Generation of *OH was carried out by the Fenton reaction using mixture of ascorbic acid, H2O2, and Fe(III)-EDTA, and *OH was detected by measuring the *OH-mediated production of degradation products of deoxyribose, which reacts with 2-thiobarbituric acid (TBA) and is relatively stable for a long time. At concentrations of 10(-10) M to 10(-3) M, guaiacol inhibited the TBA reactive substance (TBA-RS) formation in a dose-dependent manner. Phenol and formaldehyde were also found to inhibit the TBA-RS formation, but their inhibitory activities were lower than that of guaiacol. The concentrations of guaiacol, phenol, and formaldehyde needed to cause 50% inhibition of TBA-RS formation were approximately 5 x 10(-6), 5 x 10(-5), and 2 x 10(-3) M, respectively. In this reaction system, guaiacol showed no chelating reaction with ferrous ion and did not directly react with H2O2. Guaiacol also exhibited radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) stable free radical, but its scavenging activity was lower than that toward *OH. These results suggest that guaiacol is a potent scavenger of reactive oxygen radicals and that its radical scavenging activity may be associated with its effect on cell proliferation." @default.
- W2086793918 created "2016-06-24" @default.
- W2086793918 creator A5019458192 @default.
- W2086793918 creator A5038376263 @default.
- W2086793918 creator A5055025893 @default.
- W2086793918 creator A5078748985 @default.
- W2086793918 creator A5082335621 @default.
- W2086793918 date "2005-01-01" @default.
- W2086793918 modified "2023-09-23" @default.
- W2086793918 title "Hydroxyl radical scavenging effects of guaiacol used in traditional dental pulp sedation: Reaction kinetic study" @default.
- W2086793918 cites W1497717446 @default.
- W2086793918 cites W1660261394 @default.
- W2086793918 cites W1799674254 @default.
- W2086793918 cites W1966799420 @default.
- W2086793918 cites W1967585926 @default.
- W2086793918 cites W1998784580 @default.
- W2086793918 cites W2000799431 @default.
- W2086793918 cites W2004041780 @default.
- W2086793918 cites W2024716555 @default.
- W2086793918 cites W2030177086 @default.
- W2086793918 cites W2038615667 @default.
- W2086793918 cites W2038987475 @default.
- W2086793918 cites W2051496266 @default.
- W2086793918 cites W2141670884 @default.
- W2086793918 cites W2156612556 @default.
- W2086793918 doi "https://doi.org/10.2220/biomedres.26.139" @default.
- W2086793918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16152729" @default.
- W2086793918 hasPublicationYear "2005" @default.
- W2086793918 type Work @default.
- W2086793918 sameAs 2086793918 @default.
- W2086793918 citedByCount "22" @default.
- W2086793918 countsByYear W20867939182012 @default.
- W2086793918 countsByYear W20867939182013 @default.
- W2086793918 countsByYear W20867939182015 @default.
- W2086793918 countsByYear W20867939182017 @default.
- W2086793918 countsByYear W20867939182018 @default.
- W2086793918 countsByYear W20867939182019 @default.
- W2086793918 countsByYear W20867939182020 @default.
- W2086793918 countsByYear W20867939182021 @default.
- W2086793918 countsByYear W20867939182023 @default.
- W2086793918 crossrefType "journal-article" @default.
- W2086793918 hasAuthorship W2086793918A5019458192 @default.
- W2086793918 hasAuthorship W2086793918A5038376263 @default.
- W2086793918 hasAuthorship W2086793918A5055025893 @default.
- W2086793918 hasAuthorship W2086793918A5078748985 @default.
- W2086793918 hasAuthorship W2086793918A5082335621 @default.
- W2086793918 hasBestOaLocation W20867939181 @default.
- W2086793918 hasConcept C139066938 @default.
- W2086793918 hasConcept C13965031 @default.
- W2086793918 hasConcept C161790260 @default.
- W2086793918 hasConcept C178790620 @default.
- W2086793918 hasConcept C185592680 @default.
- W2086793918 hasConcept C2776778087 @default.
- W2086793918 hasConcept C2777504301 @default.
- W2086793918 hasConcept C2777702071 @default.
- W2086793918 hasConcept C2777713698 @default.
- W2086793918 hasConcept C2778004101 @default.
- W2086793918 hasConcept C2780199054 @default.
- W2086793918 hasConcept C2780829032 @default.
- W2086793918 hasConcept C2781401929 @default.
- W2086793918 hasConcept C2986274086 @default.
- W2086793918 hasConcept C31903555 @default.
- W2086793918 hasConceptScore W2086793918C139066938 @default.
- W2086793918 hasConceptScore W2086793918C13965031 @default.
- W2086793918 hasConceptScore W2086793918C161790260 @default.
- W2086793918 hasConceptScore W2086793918C178790620 @default.
- W2086793918 hasConceptScore W2086793918C185592680 @default.
- W2086793918 hasConceptScore W2086793918C2776778087 @default.
- W2086793918 hasConceptScore W2086793918C2777504301 @default.
- W2086793918 hasConceptScore W2086793918C2777702071 @default.
- W2086793918 hasConceptScore W2086793918C2777713698 @default.
- W2086793918 hasConceptScore W2086793918C2778004101 @default.
- W2086793918 hasConceptScore W2086793918C2780199054 @default.
- W2086793918 hasConceptScore W2086793918C2780829032 @default.
- W2086793918 hasConceptScore W2086793918C2781401929 @default.
- W2086793918 hasConceptScore W2086793918C2986274086 @default.
- W2086793918 hasConceptScore W2086793918C31903555 @default.
- W2086793918 hasIssue "4" @default.
- W2086793918 hasLocation W20867939181 @default.
- W2086793918 hasLocation W20867939182 @default.
- W2086793918 hasOpenAccess W2086793918 @default.
- W2086793918 hasPrimaryLocation W20867939181 @default.
- W2086793918 hasRelatedWork W134642537 @default.
- W2086793918 hasRelatedWork W1966337736 @default.
- W2086793918 hasRelatedWork W2023594870 @default.
- W2086793918 hasRelatedWork W2072592540 @default.
- W2086793918 hasRelatedWork W2107161416 @default.
- W2086793918 hasRelatedWork W2184186596 @default.
- W2086793918 hasRelatedWork W2363975772 @default.
- W2086793918 hasRelatedWork W2381986359 @default.
- W2086793918 hasRelatedWork W4205614767 @default.
- W2086793918 hasRelatedWork W4315434472 @default.
- W2086793918 hasVolume "26" @default.
- W2086793918 isParatext "false" @default.
- W2086793918 isRetracted "false" @default.
- W2086793918 magId "2086793918" @default.
- W2086793918 workType "article" @default.