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- W2086809310 abstract "<b><i>Aims:</i></b> To investigate the contribution of dysfunction of maternal hemodynamics to renal impairment in preeclampsia (PE). <b><i>Methods:</i></b> Urinary protein excretion, serum creatinine, blood urea nitrogen, uric acid, and glomerular filtration rate were assessed in 571 pregnant women with PE in addition to and noninvasive hemodynamic monitoring.<b> </b>Patients were classified into two groups: PE with renal impairment (glomerular filtration rate <90 ml/min/1.73 m<sup>2</sup>, n = 161) and PE with normal renal function (n = 410). Cut-off values for hemodynamic parameters were calculated using receiver-operating characteristic curve analysis. <b><i>Results:</i></b> Maternal systolic function and cardiac output parameters were low and peripheral resistance was high in the PE renal impairment group. Cut-off values for the hemodynamic parameters, cardiac index, cardiac output, systemic vascular resistance index, and systemic vascular resistance were 2.85 l/min/m<sup>2</sup>, 5.25 l/min, 3,014.5 dyn s cm<sup>-5</sup> m<sup>2</sup> and 1,636.0 dyn s cm<sup>-5</sup>, respectively, according to receiver-operating characteristics curves. <b><i>Conclusion:</i></b> Renal impairment in PE is associated with reduced maternal cardiac output and increased peripheral resistance." @default.
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- W2086809310 date "2013-01-01" @default.
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- W2086809310 title "Contribution of Dysfunction of Maternal Hemodynamics to Renal Impairment in Preeclampsia" @default.
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- W2086809310 doi "https://doi.org/10.1159/000353275" @default.
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