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- W2086831967 abstract "An agarose plate method for detecting human alloantibodies (inhibitors) to coagulant factor IX has been developed. The assay is based on the ability of such antisera to inhibit the coagulation of a mixture of haemophilia B plasma, normal plasma and platelet substitute in an agarose matrix. The agarose plate method was also adopted to measure levels of FIX antigen (IX:Ag) in plasma. Using this technique, 12 of 17 obligate carriers of haemophilia B demonstrated reduced levels of IX:Ag. Three of the five carriers with normal IX:Ag levels were members of kindred in which affected individuals had normal or near normal levels of IX:Ag." @default.
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- W2086831967 date "1980-02-01" @default.
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- W2086831967 title "An Agarose Plate Method for Detecting Alloantisera to Coagulant Factor IX and Factor IX Antigen" @default.
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- W2086831967 doi "https://doi.org/10.1111/j.1365-2141.1980.tb01214.x" @default.
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