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• W2086919317 abstract "Images of mastectomy breast specimens have been acquired with a bench top experimental Cone beam CT(CBCT) system. The resulting images have been segmented to model an uncompressed breast forsimulation of various CBCT techniques. To further simulate conventional or tomosynthesis mammographicimaging for comparison with the CBCT technique, a deformation technique was developed to convert theCT data for an uncompressed breast to a compressed breast without altering the breast volume or regionalbreast density. With this technique, 3D breast deformation is separated into two 2D deformations in coronaland axial views. To preserve the total breast volume and regional tissue composition, each 2D deformationstep was achieved by altering the square pixels into rectangular ones with the pixel areas unchanged and resamplingwith the original square pixels using bilinear interpolation. The compression was modeled by firststretching the breast in the superior-inferior direction in the coronal view. The image data were firstdeformed by distorting the voxels with a uniform distortion ratio. These deformed data were then deformedagain using distortion ratios varying with the breast thickness and re-sampled. The deformation procedureswere applied in the axial view to stretch the breast in the chest wall to nipple direction while shrinking it inthe mediolateral to lateral direction re-sampled and converted into data for uniform cubic voxels. Thresholdsegmentation was applied to the final deformed image data to obtain the 3D compressed breast model. Ourresults show that the original segmented CBCT image data were successfully converted into those for acompressed breast with the same volume and regional density preserved. Using this compressed breastmodel, conventional and tomosynthesis mammograms were simulated for comparison with CBCT." @default.
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• W2086919317 date "2009-02-26" @default.
• W2086919317 modified "2023-09-25" @default.
• W2086919317 title "Volume and tissue composition preserving deformation of breast CT images to simulate breast compression in mammographic imaging" @default.
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• W2086919317 doi "https://doi.org/10.1117/12.813813" @default.
• W2086919317 hasPublicationYear "2009" @default.
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