FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086924754> ?p ?o ?g. }

• W2086924754 endingPage "108" @default.
• W2086924754 startingPage "100" @default.
• W2086924754 abstract "I.c.v. administration of the octadecaneuropeptide (ODN), a peptide derived from diazepam-binding inhibitor (DBI), induces anorexigenic and anxiogenic-like actions in rodents. We have recently shown that, in goldfish, i.c.v. injection of ODN also reduces food consumption via the metabotropic endozepine receptor. However, there is little information regarding the structure of DBI and the psychophysiological roles of endozepines in fish. Therefore, in the present study, we isolated and cloned a cDNA encoding goldfish DBI. The deduced sequence exhibits high similarity with non-mammalian DBIs, and we investigated the effect of homologous ODN on psychomotor activity in goldfish. i.c.v. injection of synthetic goldfish ODN at 10 pmol/g body weight (BW) stimulated locomotor activity. Since intact goldfish placed in a tank with both black and white background areas prefers the black compartment, we developed a method for measuring the time taken for fish to move from the black to the white area. I.c.v. administration of diazepam (35 and 350 pmol/g BW) decreased, whereas i.c.v. administration of ODN (10 pmol/g BW) or the central-type benzodiazepine receptor inverse agonist FG-7142 (9 pmol/g BW) increased the time taken to move from the black to the white background area. The anxiogenic-like effect of ODN was blocked by the central-type benzodiazepine receptor antagonist flumazenil (100 pmol/g BW), but was not affected by the metabotropic endozepine receptor antagonist cyclo1-8[d-Leu5]octapeptide (100 pmol/g BW). These data indicate that ODN can potently affect locomotor and psychomotor activities in goldfish and that this action is mediated via the central-type benzodiazepine receptor-signaling pathway." @default.
• W2086924754 created "2016-06-24" @default.
• W2086924754 creator A5003657445 @default.
• W2086924754 creator A5010175476 @default.
• W2086924754 creator A5015125277 @default.
• W2086924754 creator A5020999411 @default.
• W2086924754 creator A5039475736 @default.
• W2086924754 creator A5055539271 @default.
• W2086924754 creator A5068017055 @default.
• W2086924754 creator A5077623245 @default.
• W2086924754 creator A5087359258 @default.
• W2086924754 date "2011-05-01" @default.
• W2086924754 modified "2023-10-06" @default.
• W2086924754 title "The octadecaneuropeptide exerts an anxiogenic-like action in goldfish" @default.
• W2086924754 cites W129451783 @default.
• W2086924754 cites W1483530097 @default.
• W2086924754 cites W1545231006 @default.
• W2086924754 cites W1595231167 @default.
• W2086924754 cites W1652929328 @default.
• W2086924754 cites W1662900998 @default.
• W2086924754 cites W1969304868 @default.
• W2086924754 cites W1969627429 @default.
• W2086924754 cites W1972559823 @default.
• W2086924754 cites W1972939738 @default.
• W2086924754 cites W1973033123 @default.
• W2086924754 cites W1975995786 @default.
• W2086924754 cites W1977263736 @default.
• W2086924754 cites W1977384673 @default.
• W2086924754 cites W1983550360 @default.
• W2086924754 cites W1990077563 @default.
• W2086924754 cites W1990256902 @default.
• W2086924754 cites W1991073855 @default.
• W2086924754 cites W2004368389 @default.
• W2086924754 cites W2005298105 @default.
• W2086924754 cites W2006000052 @default.
• W2086924754 cites W2007874342 @default.
• W2086924754 cites W2012550935 @default.
• W2086924754 cites W2018257078 @default.
• W2086924754 cites W2023067893 @default.
• W2086924754 cites W2026629863 @default.
• W2086924754 cites W2027805085 @default.
• W2086924754 cites W2028234869 @default.
• W2086924754 cites W2033829608 @default.
• W2086924754 cites W2039215531 @default.
• W2086924754 cites W2055226626 @default.
• W2086924754 cites W2066051960 @default.
• W2086924754 cites W2069748159 @default.
• W2086924754 cites W2076680451 @default.
• W2086924754 cites W2079177982 @default.
• W2086924754 cites W2080082695 @default.
• W2086924754 cites W2080359769 @default.
• W2086924754 cites W2081710585 @default.
• W2086924754 cites W2082070124 @default.
• W2086924754 cites W2082723143 @default.
• W2086924754 cites W2083859487 @default.
• W2086924754 cites W2085358666 @default.
• W2086924754 cites W2087834131 @default.
• W2086924754 cites W2089813747 @default.
• W2086924754 cites W2090585484 @default.
• W2086924754 cites W2091310001 @default.
• W2086924754 cites W2091662811 @default.
• W2086924754 cites W2108222684 @default.
• W2086924754 cites W2109798234 @default.
• W2086924754 cites W2126749853 @default.
• W2086924754 cites W2156979070 @default.
• W2086924754 cites W2160186899 @default.
• W2086924754 cites W2162700737 @default.
• W2086924754 cites W2162954304 @default.
• W2086924754 cites W2900714423 @default.
• W2086924754 cites W4238423036 @default.
• W2086924754 cites W4376999358 @default.
• W2086924754 doi "https://doi.org/10.1016/j.neuroscience.2011.02.058" @default.
• W2086924754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21382452" @default.
• W2086924754 hasPublicationYear "2011" @default.
• W2086924754 type Work @default.
• W2086924754 sameAs 2086924754 @default.
• W2086924754 citedByCount "26" @default.
• W2086924754 countsByYear W20869247542012 @default.
• W2086924754 countsByYear W20869247542013 @default.
• W2086924754 countsByYear W20869247542014 @default.
• W2086924754 countsByYear W20869247542015 @default.
• W2086924754 countsByYear W20869247542016 @default.
• W2086924754 countsByYear W20869247542017 @default.
• W2086924754 countsByYear W20869247542018 @default.
• W2086924754 countsByYear W20869247542019 @default.
• W2086924754 countsByYear W20869247542020 @default.
• W2086924754 countsByYear W20869247542021 @default.
• W2086924754 countsByYear W20869247542022 @default.
• W2086924754 countsByYear W20869247542023 @default.
• W2086924754 crossrefType "journal-article" @default.
• W2086924754 hasAuthorship W2086924754A5003657445 @default.
• W2086924754 hasAuthorship W2086924754A5010175476 @default.
• W2086924754 hasAuthorship W2086924754A5015125277 @default.
• W2086924754 hasAuthorship W2086924754A5020999411 @default.
• W2086924754 hasAuthorship W2086924754A5039475736 @default.
• W2086924754 hasAuthorship W2086924754A5055539271 @default.
• W2086924754 hasAuthorship W2086924754A5068017055 @default.
• W2086924754 hasAuthorship W2086924754A5077623245 @default.

• next