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- W2086943635 abstract "Abstract Evidence has suggested that there is a reciprocal relationship between ammonia and uric acid excretion in man. A decrease in ammonia excretion has been described in gout. The administration of ammonium chloride has produced a decrement in uric acid excretion. Studies were conducted to determine if these observations were causally related. Nine patients with gout were studied under controlled conditions on a metabolic ward. Ammonia, titratable acid and uric acid excretion were measured following ammonium chloride administration before and after reduction of the renal urate load by allopurinol. Data were analyzed by multilinear regression and path analysis. The results indicate that ammonia excretion was independent of uric acid excretion." @default.
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- W2086943635 date "1969-06-01" @default.
- W2086943635 modified "2023-09-27" @default.
- W2086943635 title "Effect of allopurinol on urinary ammonia excretion in patients with gout" @default.
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- W2086943635 doi "https://doi.org/10.1016/0026-0495(69)90145-0" @default.
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