FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2086971492> ?p ?o ?g. }

• W2086971492 endingPage "357" @default.
• W2086971492 startingPage "350" @default.
• W2086971492 abstract "Cardiovascular disease (CVD) is associated with cognitive deficits even in the absence of stroke. We examined the relationship between cardiac performance, as measured by cardiac output (CO) and ejection fraction (EF), and brain activity during a verbal working memory (VWM) task in elderly CVD patients who tend to be at increased risk for vascular cognitive impairments. Seventeen patients were recruited from a cohort participating in an ongoing prospective study examining the effects of CVD on cognitive function in the elderly. Participants were diagnosed with CVD (age 68±8) and completed a 2-back VWM task in a 1.5T fMRI paradigm. CO and EF were calculated from echocardiogram measures. Task-related activation was averaged in a priori regions of interest. The relationship between CO, EF, and 2-back-related activity was modeled using partial correlations (two-tailed p<.05) controlling for age and 2-back accuracy. All participants were globally cognitively intact as indicated by Mini-Mental Status Exam and Dementia Rating Scale scores. Mean accuracy on the 2-back was 78±9% while reaction time averaged 1,027±192 ms. Mean CO and EF values showed a large range (CO: 3.55 to 6.31; EF: 0.36 to 0.76) but average values were within the normal range. After controlling for age and 2-back accuracy, lower EF was related to decrease in left insula activity (r=0.61, p=0.03). There were trends for EF to be related to accuracy (r=0.47, p=0.09) and reaction time (r=-0.48, p=0.09). CO was also related to insula activity (r=0.60, p=0.04) and activity in the supplementary motor area activity (r=0.66, p=0.01). Cardiac performance was related to decreased efficiency in task related brain areas and tended to be related to performance on a VWM task in elderly patients with CVD. Results have implications for a line of investigation indicating that cardiac and systemic vascular indices could be used as proxy measures to examine mechanisms of cerebrovascular dysfunction in the elderly." @default.
• W2086971492 created "2016-06-24" @default.
• W2086971492 creator A5021789074 @default.
• W2086971492 creator A5030230239 @default.
• W2086971492 creator A5035290107 @default.
• W2086971492 creator A5048589387 @default.
• W2086971492 creator A5063416978 @default.
• W2086971492 creator A5065822809 @default.
• W2086971492 creator A5066302335 @default.
• W2086971492 creator A5072862594 @default.
• W2086971492 creator A5075786587 @default.
• W2086971492 date "2009-08-15" @default.
• W2086971492 modified "2023-10-13" @default.
• W2086971492 title "A fMRI Study of Verbal Working Memory, Cardiac Output, and Ejection Fraction in Elderly Patients with Cardiovascular Disease" @default.
• W2086971492 cites W1510737382 @default.
• W2086971492 cites W1963526367 @default.
• W2086971492 cites W1963616846 @default.
• W2086971492 cites W1974694686 @default.
• W2086971492 cites W2001025157 @default.
• W2086971492 cites W2018007042 @default.
• W2086971492 cites W2020782371 @default.
• W2086971492 cites W2023280641 @default.
• W2086971492 cites W2024323643 @default.
• W2086971492 cites W2025799328 @default.
• W2086971492 cites W2030700713 @default.
• W2086971492 cites W2039043072 @default.
• W2086971492 cites W2040090425 @default.
• W2086971492 cites W2040865591 @default.
• W2086971492 cites W2048943469 @default.
• W2086971492 cites W2057823018 @default.
• W2086971492 cites W2061353398 @default.
• W2086971492 cites W2065927779 @default.
• W2086971492 cites W2089974145 @default.
• W2086971492 cites W2090553836 @default.
• W2086971492 cites W2092368495 @default.
• W2086971492 cites W2101099004 @default.
• W2086971492 cites W2102811819 @default.
• W2086971492 cites W2105558714 @default.
• W2086971492 cites W2117140276 @default.
• W2086971492 cites W2122281432 @default.
• W2086971492 cites W2126685399 @default.
• W2086971492 cites W2127105874 @default.
• W2086971492 cites W2134485345 @default.
• W2086971492 cites W2142360036 @default.
• W2086971492 cites W2142426851 @default.
• W2086971492 cites W2146311773 @default.
• W2086971492 cites W2157813392 @default.
• W2086971492 cites W2158894485 @default.
• W2086971492 cites W2167507724 @default.
• W2086971492 cites W4253781094 @default.
• W2086971492 cites W4300796877 @default.
• W2086971492 doi "https://doi.org/10.1007/s11682-009-9077-0" @default.
• W2086971492 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3514458" @default.
• W2086971492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23227137" @default.
• W2086971492 hasPublicationYear "2009" @default.
• W2086971492 type Work @default.
• W2086971492 sameAs 2086971492 @default.
• W2086971492 citedByCount "16" @default.
• W2086971492 countsByYear W20869714922013 @default.
• W2086971492 countsByYear W20869714922015 @default.
• W2086971492 countsByYear W20869714922018 @default.
• W2086971492 countsByYear W20869714922020 @default.
• W2086971492 countsByYear W20869714922021 @default.
• W2086971492 countsByYear W20869714922022 @default.
• W2086971492 countsByYear W20869714922023 @default.
• W2086971492 crossrefType "journal-article" @default.
• W2086971492 hasAuthorship W2086971492A5021789074 @default.
• W2086971492 hasAuthorship W2086971492A5030230239 @default.
• W2086971492 hasAuthorship W2086971492A5035290107 @default.
• W2086971492 hasAuthorship W2086971492A5048589387 @default.
• W2086971492 hasAuthorship W2086971492A5063416978 @default.
• W2086971492 hasAuthorship W2086971492A5065822809 @default.
• W2086971492 hasAuthorship W2086971492A5066302335 @default.
• W2086971492 hasAuthorship W2086971492A5072862594 @default.
• W2086971492 hasAuthorship W2086971492A5075786587 @default.
• W2086971492 hasBestOaLocation W20869714922 @default.
• W2086971492 hasConcept C118552586 @default.
• W2086971492 hasConcept C126322002 @default.
• W2086971492 hasConcept C14216870 @default.
• W2086971492 hasConcept C15744967 @default.
• W2086971492 hasConcept C164705383 @default.
• W2086971492 hasConcept C169900460 @default.
• W2086971492 hasConcept C185711340 @default.
• W2086971492 hasConcept C21963081 @default.
• W2086971492 hasConcept C2778198053 @default.
• W2086971492 hasConcept C2779134260 @default.
• W2086971492 hasConcept C2779483572 @default.
• W2086971492 hasConcept C548259974 @default.
• W2086971492 hasConcept C71924100 @default.
• W2086971492 hasConcept C72563966 @default.
• W2086971492 hasConcept C78085059 @default.
• W2086971492 hasConceptScore W2086971492C118552586 @default.
• W2086971492 hasConceptScore W2086971492C126322002 @default.
• W2086971492 hasConceptScore W2086971492C14216870 @default.
• W2086971492 hasConceptScore W2086971492C15744967 @default.
• W2086971492 hasConceptScore W2086971492C164705383 @default.
• W2086971492 hasConceptScore W2086971492C169900460 @default.
• W2086971492 hasConceptScore W2086971492C185711340 @default.

• next