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- W2086987796 abstract "Purpose of review To comment on the most recent findings regarding the clinical impact of single and tandem autologous and miniallogeneic stem cell transplantation in de novo multiple myeloma. Recent findings The superiority of autologous stem cell transplantation compared with conventional chemotherapy has been confirmed in patients with newly diagnosed multiple myeloma. It has also been demonstrated that the best conditioning regimen before autologous stem cell transplantation is melphalan 200 mg/m2. The impact of tandem transplants is under investigation, but preliminary results from several groups show a higher event-free survival rate, and in one large trial, a higher survival rate, in patients receiving two transplants. The role of miniallogeneic transplantation and the feasibility up front to all eligible patients must be determined. Summary High-dose therapy and autologous stem cell transplantation is the standard of care in patients younger than 65 years with de novo multiple myeloma. The role of tandem autologous transplantation and of miniallogeneic stem cell transplantation in the same population of patients must be determined." @default.
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- W2086987796 date "2004-03-01" @default.
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- W2086987796 title "Hematopoietic cell transplantation in multiple myeloma" @default.
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- W2086987796 doi "https://doi.org/10.1097/00075200-200403000-00009" @default.
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