Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087010989> ?p ?o ?g. }
- W2087010989 abstract "Non-alcoholic fatty liver disease is now recognized as a cause of potentially progressive liver damage, posing patients at risk of advanced liver failure. Unfortunately, the natural history of disease is only partly known, the disease is slowly progressive and therapeutic outcomes are difficult to define. These factors have limited therapeutic trials to pilot studies, and very few randomized-controlled studies are available. The concept that insulin-resistance, coupled with oxidative stress, may be the underlying mechanism responsible for fat accumulation and disease progression points to insulin-sensitizing agents (metformin, thiazolidinediones) as the most promising drugs. They proved effective in reducing enzyme levels in the short period, but very limited information is available on liver histology, not to say progression to liver cell failure. Large, long-term, placebo-controlled randomized studies are eagerly awaited. Outside controlled studies, nutritional counselling and physical exercise aimed at moderate weight loss remain the basis of any therapeutic intervention." @default.
- W2087010989 created "2016-06-24" @default.
- W2087010989 creator A5018793372 @default.
- W2087010989 creator A5039273685 @default.
- W2087010989 creator A5039389628 @default.
- W2087010989 creator A5083985420 @default.
- W2087010989 date "2004-12-01" @default.
- W2087010989 modified "2023-09-23" @default.
- W2087010989 title "Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): treatment" @default.
- W2087010989 cites W1436423618 @default.
- W2087010989 cites W1522553235 @default.
- W2087010989 cites W1530129189 @default.
- W2087010989 cites W1770257749 @default.
- W2087010989 cites W1825742435 @default.
- W2087010989 cites W1964463962 @default.
- W2087010989 cites W1970570571 @default.
- W2087010989 cites W1976173209 @default.
- W2087010989 cites W1986349550 @default.
- W2087010989 cites W1988981256 @default.
- W2087010989 cites W1994194872 @default.
- W2087010989 cites W1996641308 @default.
- W2087010989 cites W1998678732 @default.
- W2087010989 cites W2002502142 @default.
- W2087010989 cites W2003403665 @default.
- W2087010989 cites W2006591225 @default.
- W2087010989 cites W2016810904 @default.
- W2087010989 cites W2019151036 @default.
- W2087010989 cites W2019280401 @default.
- W2087010989 cites W2028236765 @default.
- W2087010989 cites W2029811522 @default.
- W2087010989 cites W2040538211 @default.
- W2087010989 cites W2045911846 @default.
- W2087010989 cites W2061072369 @default.
- W2087010989 cites W2062663604 @default.
- W2087010989 cites W2068065991 @default.
- W2087010989 cites W2076204761 @default.
- W2087010989 cites W2082299629 @default.
- W2087010989 cites W2084672746 @default.
- W2087010989 cites W2086018530 @default.
- W2087010989 cites W2087011218 @default.
- W2087010989 cites W2087389370 @default.
- W2087010989 cites W2091045022 @default.
- W2087010989 cites W2092860379 @default.
- W2087010989 cites W2097706636 @default.
- W2087010989 cites W2098765345 @default.
- W2087010989 cites W2100093159 @default.
- W2087010989 cites W2102061487 @default.
- W2087010989 cites W2104135649 @default.
- W2087010989 cites W2106991663 @default.
- W2087010989 cites W2114707445 @default.
- W2087010989 cites W2129170737 @default.
- W2087010989 cites W2130742202 @default.
- W2087010989 cites W2135385594 @default.
- W2087010989 cites W2139112405 @default.
- W2087010989 cites W2142844314 @default.
- W2087010989 cites W2142912849 @default.
- W2087010989 cites W2158468809 @default.
- W2087010989 cites W2160234571 @default.
- W2087010989 cites W2178920245 @default.
- W2087010989 doi "https://doi.org/10.1016/j.bpg.2004.06.025" @default.
- W2087010989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15561641" @default.
- W2087010989 hasPublicationYear "2004" @default.
- W2087010989 type Work @default.
- W2087010989 sameAs 2087010989 @default.
- W2087010989 citedByCount "31" @default.
- W2087010989 countsByYear W20870109892012 @default.
- W2087010989 countsByYear W20870109892014 @default.
- W2087010989 countsByYear W20870109892015 @default.
- W2087010989 countsByYear W20870109892016 @default.
- W2087010989 countsByYear W20870109892017 @default.
- W2087010989 countsByYear W20870109892018 @default.
- W2087010989 crossrefType "journal-article" @default.
- W2087010989 hasAuthorship W2087010989A5018793372 @default.
- W2087010989 hasAuthorship W2087010989A5039273685 @default.
- W2087010989 hasAuthorship W2087010989A5039389628 @default.
- W2087010989 hasAuthorship W2087010989A5083985420 @default.
- W2087010989 hasConcept C126322002 @default.
- W2087010989 hasConcept C2777391703 @default.
- W2087010989 hasConcept C2778772119 @default.
- W2087010989 hasConcept C2779134260 @default.
- W2087010989 hasConcept C2779306644 @default.
- W2087010989 hasConcept C2779478299 @default.
- W2087010989 hasConcept C2780323712 @default.
- W2087010989 hasConcept C71924100 @default.
- W2087010989 hasConcept C90924648 @default.
- W2087010989 hasConceptScore W2087010989C126322002 @default.
- W2087010989 hasConceptScore W2087010989C2777391703 @default.
- W2087010989 hasConceptScore W2087010989C2778772119 @default.
- W2087010989 hasConceptScore W2087010989C2779134260 @default.
- W2087010989 hasConceptScore W2087010989C2779306644 @default.
- W2087010989 hasConceptScore W2087010989C2779478299 @default.
- W2087010989 hasConceptScore W2087010989C2780323712 @default.
- W2087010989 hasConceptScore W2087010989C71924100 @default.
- W2087010989 hasConceptScore W2087010989C90924648 @default.
- W2087010989 hasLocation W20870109891 @default.
- W2087010989 hasLocation W20870109892 @default.
- W2087010989 hasOpenAccess W2087010989 @default.
- W2087010989 hasPrimaryLocation W20870109891 @default.
- W2087010989 hasRelatedWork W1996641308 @default.
- W2087010989 hasRelatedWork W1997011922 @default.