Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087015880> ?p ?o ?g. }
- W2087015880 endingPage "1077" @default.
- W2087015880 startingPage "1077" @default.
- W2087015880 abstract "GLUCOCORTICOIDS are commonly used in obstetric practice, both for maternal immunosuppression and for shortterm treatment of the fetus, usually to accelerate lung maturation when there is threatened preterm delivery. The immediate benefits of short-term prepartum glucocorticoid therapy in maturing the fetal lung and reducing neonatal mortality are clearly supported by controlled studies.<sup>1,2</sup>Recently, long-term prenatal therapy of fetuses potentially affected with congenital adrenal hyperplasia (CAH) has been advocated,<sup>3,4</sup>but the safety of this experimental therapy has not been established in rigorously controlled trials. See also p 1073. Congenital adrenal hyperplasia is a recessively inherited disease in which a disordered steroidogenic enzyme, usually P450c21 (21-hydroxylase), diverts adrenal steroid synthesis away from cortisol toward androgens.<sup>5</sup>In utero, low fetal plasma cortisol levels stimulate increased corticotropin (ACTH) secretion, which in turn stimulates further adrenal steroidogenesis, resulting in even more androgen synthesis. In an XY male fetus, these adrenal androgens have" @default.
- W2087015880 created "2016-06-24" @default.
- W2087015880 creator A5064304317 @default.
- W2087015880 creator A5064575852 @default.
- W2087015880 date "1997-04-02" @default.
- W2087015880 modified "2023-10-17" @default.
- W2087015880 title "How Safe Is Long-term Prenatal Glucocorticoid Treatment?" @default.
- W2087015880 cites W108496218 @default.
- W2087015880 cites W127526507 @default.
- W2087015880 cites W157431801 @default.
- W2087015880 cites W1849290362 @default.
- W2087015880 cites W1933480820 @default.
- W2087015880 cites W1968075657 @default.
- W2087015880 cites W1974086094 @default.
- W2087015880 cites W1987610912 @default.
- W2087015880 cites W1996115861 @default.
- W2087015880 cites W2009788880 @default.
- W2087015880 cites W2013222700 @default.
- W2087015880 cites W2014212152 @default.
- W2087015880 cites W2017666356 @default.
- W2087015880 cites W2021131551 @default.
- W2087015880 cites W2025585930 @default.
- W2087015880 cites W2034652601 @default.
- W2087015880 cites W2039911691 @default.
- W2087015880 cites W2047107705 @default.
- W2087015880 cites W2049986152 @default.
- W2087015880 cites W2061571315 @default.
- W2087015880 cites W2066338366 @default.
- W2087015880 cites W2070899628 @default.
- W2087015880 cites W2071878822 @default.
- W2087015880 cites W2076822580 @default.
- W2087015880 cites W2081276639 @default.
- W2087015880 cites W2091250500 @default.
- W2087015880 cites W2093826550 @default.
- W2087015880 cites W2095398283 @default.
- W2087015880 cites W2096572993 @default.
- W2087015880 cites W2096601431 @default.
- W2087015880 cites W2105924023 @default.
- W2087015880 cites W2113376917 @default.
- W2087015880 cites W2115410011 @default.
- W2087015880 cites W2120543890 @default.
- W2087015880 cites W2124145052 @default.
- W2087015880 cites W2164585711 @default.
- W2087015880 cites W2317609295 @default.
- W2087015880 cites W2398317637 @default.
- W2087015880 cites W2398640658 @default.
- W2087015880 cites W2999510508 @default.
- W2087015880 cites W3147680129 @default.
- W2087015880 doi "https://doi.org/10.1001/jama.1997.03540370067039" @default.
- W2087015880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9091698" @default.
- W2087015880 hasPublicationYear "1997" @default.
- W2087015880 type Work @default.
- W2087015880 sameAs 2087015880 @default.
- W2087015880 citedByCount "94" @default.
- W2087015880 countsByYear W20870158802012 @default.
- W2087015880 countsByYear W20870158802013 @default.
- W2087015880 countsByYear W20870158802014 @default.
- W2087015880 countsByYear W20870158802015 @default.
- W2087015880 countsByYear W20870158802016 @default.
- W2087015880 countsByYear W20870158802017 @default.
- W2087015880 countsByYear W20870158802018 @default.
- W2087015880 countsByYear W20870158802019 @default.
- W2087015880 countsByYear W20870158802020 @default.
- W2087015880 countsByYear W20870158802021 @default.
- W2087015880 countsByYear W20870158802023 @default.
- W2087015880 crossrefType "journal-article" @default.
- W2087015880 hasAuthorship W2087015880A5064304317 @default.
- W2087015880 hasAuthorship W2087015880A5064575852 @default.
- W2087015880 hasConcept C126322002 @default.
- W2087015880 hasConcept C134018914 @default.
- W2087015880 hasConcept C172680121 @default.
- W2087015880 hasConcept C201614185 @default.
- W2087015880 hasConcept C2777391703 @default.
- W2087015880 hasConcept C2777767042 @default.
- W2087015880 hasConcept C2777911890 @default.
- W2087015880 hasConcept C2779234561 @default.
- W2087015880 hasConcept C2779306644 @default.
- W2087015880 hasConcept C2780841215 @default.
- W2087015880 hasConcept C2910605048 @default.
- W2087015880 hasConcept C3018442814 @default.
- W2087015880 hasConcept C54355233 @default.
- W2087015880 hasConcept C71315377 @default.
- W2087015880 hasConcept C71924100 @default.
- W2087015880 hasConcept C86803240 @default.
- W2087015880 hasConceptScore W2087015880C126322002 @default.
- W2087015880 hasConceptScore W2087015880C134018914 @default.
- W2087015880 hasConceptScore W2087015880C172680121 @default.
- W2087015880 hasConceptScore W2087015880C201614185 @default.
- W2087015880 hasConceptScore W2087015880C2777391703 @default.
- W2087015880 hasConceptScore W2087015880C2777767042 @default.
- W2087015880 hasConceptScore W2087015880C2777911890 @default.
- W2087015880 hasConceptScore W2087015880C2779234561 @default.
- W2087015880 hasConceptScore W2087015880C2779306644 @default.
- W2087015880 hasConceptScore W2087015880C2780841215 @default.
- W2087015880 hasConceptScore W2087015880C2910605048 @default.
- W2087015880 hasConceptScore W2087015880C3018442814 @default.
- W2087015880 hasConceptScore W2087015880C54355233 @default.
- W2087015880 hasConceptScore W2087015880C71315377 @default.