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• W2087032518 abstract "Epidermal growth factor receptor (EGFR) exists in the nucleus of highly proliferative cells where it functions as a transcription factor. Although EGFR has transactivational activity, it lacks a DNA binding domain and, therefore, may require a DNA binding transcription cofactor for its transcriptional function. Here, we report that EGFR physically interacts with signal transducers and activators of transcription 3 (STAT3) in the nucleus, leading to transcriptional activation of inducible nitric oxide synthase (iNOS). In breast carcinomas, nuclear EGFR positively correlates with iNOS. This study describes a mode of transcriptional control involving cooperated efforts of STAT3 and nuclear EGFR. Our work suggests that the deregulated iNOS/NO pathway may partly contribute to the malignant biology of tumor cells with high levels of nuclear EGFR and STAT3." @default.
• W2087032518 created "2016-06-24" @default.
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• W2087032518 date "2005-06-01" @default.
• W2087032518 modified "2023-10-10" @default.
• W2087032518 title "Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway" @default.
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• W2087032518 cites W1523347226 @default.
• W2087032518 cites W1567148937 @default.
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• W2087032518 doi "https://doi.org/10.1016/j.ccr.2005.05.007" @default.
• W2087032518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15950906" @default.
• W2087032518 hasPublicationYear "2005" @default.
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