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- W2087115532 abstract "Inflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the gut, which lead to significant morbidity and impaired quality of life (QoL) in sufferers, without generally affecting mortality. Despite CD and UC being chronic, life-long illnesses, most medical management is directed at acute flares of disease. Moreover, with more intensive medical therapy and the development of biological therapy, there is a risk that management will become even more narrowly focused on acute care, and be directed only at those with more severe disease, rather than encompassing all sufferers and addressing important non-acute issues. This imbalance of concentration of medical attention on 'high-end' care is in part driven by the need to perform and publish randomized clinical trials of newer therapies to obtain registration and licensing for these agents, which thus occupy a large proportion of the recent IBD treatment literature. This leads to less attention on relatively 'low-technology' issues including: (i) the psychosocial burden of chronic disease, QoL and specific psychological comorbidities; (ii) comorbidity with functional gastrointestinal disorders (FGIDs); (iii) maintenance therapy, monitoring and compliance; (iv) smoking (with regard to CD); (v) sexuality, fertility, family planning and pregnancy; and (vi) iron deficiency and anaemia. We propose these to be the 'Un-promoted Issues' in IBD and review the importance and treatment of each of these in the current management of IBD." @default.
- W2087115532 created "2016-06-24" @default.
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- W2087115532 creator A5021107426 @default.
- W2087115532 creator A5034931964 @default.
- W2087115532 creator A5038076307 @default.
- W2087115532 date "2010-03-01" @default.
- W2087115532 modified "2023-10-16" @default.
- W2087115532 title "Un-promoted issues in inflammatory bowel disease: opportunities to optimize care" @default.
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- W2087115532 doi "https://doi.org/10.1111/j.1445-5994.2009.02110.x" @default.
- W2087115532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19849744" @default.
- W2087115532 hasPublicationYear "2010" @default.
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