Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087127816> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2087127816 endingPage "212" @default.
- W2087127816 startingPage "205" @default.
- W2087127816 abstract "Clonal PC12 rat pheochromocytoma cells were sequentially incubated with 125I-labeled nerve growth factor and the photoreactive bifunctional agent hydroxysuccinimidyl-p-azidobenzoate. This treatment effected the crosslinking of 125I nerve growth factor to a PC12 cell component that exhibits an apparent Mr = 148 000-158 000, and consists of a single polypeptide chain with internal disulfide bonds. The amount of label associated with this Mr = 148 000-158 000 species was proportional to the degree of occupancy of nerve growth factor receptors by 125I-labeled nerve growth factor. Affinity labeling of this species was inhibited by the presence of 0.2 microM unlabeled nerve growth factor during incubation of PC12 cells with 125I nerve growth factor. In membranes prepared from PC12 cells hydroxysuccinimidyl-p-azidobenzoate effected the crosslinking of 125I-labeled nerve growth factor to an Mr = 120 000-130 000 species but not to the Mr = 148 000-158 000 component observed in intact cells. The kinetics of 125I nerve growth factor affinity labeling of the Mr = 148 000-158 000 species closely paralleled the time-course of 125I nerve growth factor association to two kinetically distinct forms of nerve growth factor receptors in PC12 cells. The data indicate that the Mr = 148 000-158 000 species affinity-labeled by 125I nerve growth factor is the native form of a component associated with kinetically different nerve growth factor receptors in PC12 cells." @default.
- W2087127816 created "2016-06-24" @default.
- W2087127816 creator A5040819652 @default.
- W2087127816 creator A5047612906 @default.
- W2087127816 creator A5055628562 @default.
- W2087127816 creator A5085687728 @default.
- W2087127816 date "1982-12-01" @default.
- W2087127816 modified "2023-10-03" @default.
- W2087127816 title "Affinity labeling of a nerve growth factor receptor component on rat pheochromocytoma (PC12) cells" @default.
- W2087127816 cites W1486351035 @default.
- W2087127816 cites W1508807714 @default.
- W2087127816 cites W1520451556 @default.
- W2087127816 cites W1523972021 @default.
- W2087127816 cites W1564953704 @default.
- W2087127816 cites W1567148937 @default.
- W2087127816 cites W1568118221 @default.
- W2087127816 cites W1592445058 @default.
- W2087127816 cites W1992623778 @default.
- W2087127816 cites W2040796522 @default.
- W2087127816 cites W2073879684 @default.
- W2087127816 cites W2080669192 @default.
- W2087127816 cites W2082192837 @default.
- W2087127816 cites W2100837269 @default.
- W2087127816 cites W22895445 @default.
- W2087127816 cites W3105898142 @default.
- W2087127816 cites W4240350114 @default.
- W2087127816 doi "https://doi.org/10.1016/0005-2736(82)90488-6" @default.
- W2087127816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6295482" @default.
- W2087127816 hasPublicationYear "1982" @default.
- W2087127816 type Work @default.
- W2087127816 sameAs 2087127816 @default.
- W2087127816 citedByCount "26" @default.
- W2087127816 countsByYear W20871278162014 @default.
- W2087127816 crossrefType "journal-article" @default.
- W2087127816 hasAuthorship W2087127816A5040819652 @default.
- W2087127816 hasAuthorship W2087127816A5047612906 @default.
- W2087127816 hasAuthorship W2087127816A5055628562 @default.
- W2087127816 hasAuthorship W2087127816A5085687728 @default.
- W2087127816 hasConcept C121332964 @default.
- W2087127816 hasConcept C12554922 @default.
- W2087127816 hasConcept C126322002 @default.
- W2087127816 hasConcept C134018914 @default.
- W2087127816 hasConcept C148898269 @default.
- W2087127816 hasConcept C170493617 @default.
- W2087127816 hasConcept C185592680 @default.
- W2087127816 hasConcept C25642318 @default.
- W2087127816 hasConcept C2775960820 @default.
- W2087127816 hasConcept C2778423431 @default.
- W2087127816 hasConcept C55493867 @default.
- W2087127816 hasConcept C62520636 @default.
- W2087127816 hasConcept C71924100 @default.
- W2087127816 hasConcept C86803240 @default.
- W2087127816 hasConcept C95444343 @default.
- W2087127816 hasConceptScore W2087127816C121332964 @default.
- W2087127816 hasConceptScore W2087127816C12554922 @default.
- W2087127816 hasConceptScore W2087127816C126322002 @default.
- W2087127816 hasConceptScore W2087127816C134018914 @default.
- W2087127816 hasConceptScore W2087127816C148898269 @default.
- W2087127816 hasConceptScore W2087127816C170493617 @default.
- W2087127816 hasConceptScore W2087127816C185592680 @default.
- W2087127816 hasConceptScore W2087127816C25642318 @default.
- W2087127816 hasConceptScore W2087127816C2775960820 @default.
- W2087127816 hasConceptScore W2087127816C2778423431 @default.
- W2087127816 hasConceptScore W2087127816C55493867 @default.
- W2087127816 hasConceptScore W2087127816C62520636 @default.
- W2087127816 hasConceptScore W2087127816C71924100 @default.
- W2087127816 hasConceptScore W2087127816C86803240 @default.
- W2087127816 hasConceptScore W2087127816C95444343 @default.
- W2087127816 hasIssue "1" @default.
- W2087127816 hasLocation W20871278161 @default.
- W2087127816 hasLocation W20871278162 @default.
- W2087127816 hasOpenAccess W2087127816 @default.
- W2087127816 hasPrimaryLocation W20871278161 @default.
- W2087127816 hasRelatedWork W1999660566 @default.
- W2087127816 hasRelatedWork W2026017212 @default.
- W2087127816 hasRelatedWork W2034205456 @default.
- W2087127816 hasRelatedWork W2034583712 @default.
- W2087127816 hasRelatedWork W2037200938 @default.
- W2087127816 hasRelatedWork W2063619316 @default.
- W2087127816 hasRelatedWork W2074821979 @default.
- W2087127816 hasRelatedWork W2126532023 @default.
- W2087127816 hasRelatedWork W2169225653 @default.
- W2087127816 hasRelatedWork W2171223757 @default.
- W2087127816 hasVolume "693" @default.
- W2087127816 isParatext "false" @default.
- W2087127816 isRetracted "false" @default.
- W2087127816 magId "2087127816" @default.
- W2087127816 workType "article" @default.