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- W2087130282 abstract "Renal involvement and hypocomplementemia in mixed connective tissue disease are reported to be rare. A patient is described here with mixed connective tissue disease and persistently low serum C'3 levels in whom renal insufficiency and nephrotic syndrome developed secondary to immune-complex glomerulonephritis. Light microscopy of the renal biopsy specimen showed predominantly a membranous lesion. Immunofluorescent staining showed granular deposition along the basement membrane of immunoglobulin G, immunoglobulin M, fibrinogen and C3. Electron microscopy showed numerous electron-dense deposits along the glomerular capillary membrane and in the mesangium." @default.
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- W2087130282 date "1977-05-01" @default.
- W2087130282 modified "2023-09-26" @default.
- W2087130282 title "Immune-complex glomerulonephritis in a patient with mixed connective tissue disease" @default.
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- W2087130282 doi "https://doi.org/10.1016/0002-9343(77)90880-4" @default.
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