FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087203476> ?p ?o ?g. }

• W2087203476 endingPage "504" @default.
• W2087203476 startingPage "495" @default.
• W2087203476 abstract "BACKGROUND: The rare Hr B – phenotype is encoded by the (C)ce s haplotype when present at the homozygous state. This haplotype contains two altered genes: a hybrid RHD‐CE‐D s gene segregated with a ce s allele of RHCE (733C>G and 1006G>T substitutions in Exon 5 and Exon 7 respectively). The aim of this study was to further investigate the molecular background of the (C)ce s haplotype. STUDY DESIGN AND METHODS: Twelve individuals with depressed C and/or depressed e phenotype were selected from their genomic DNA analysis showing both 733C>G and 1006G>T substitutions. Phenotypic expression of low‐ and high‐prevalence Rh antigens was studied. Complete sequences of RHD and RHCE transcripts were analyzed when obtained. RESULTS: A new hybrid RHD‐CE‐D s gene (Exons 1 and 2; complete Exon 3; Exons 8, 9, and 10 from RHD; and Exons 4 through 7 from RHCE ) segregated with a ce s allele, which genomic organization was almost identical to that of the classical (C)ce s haplotype, is described. The two different (C)ce s haplotypes encoded two different patterns of Rh antigen expression. Although both encoded weak e, VS, and did not produce D, V, hr B , or Hr B antigens, the new haplotype encoded a much weaker C antigen and red blood cells lacked expression of Rh42, in contrast to the classic (C)ce s haplotype. CONCLUSION: The study showed the heterogeneity of the molecular background of the weak C, VS+, hr B –, Hr B – phenotype in the black population. The screening of blood donors in this population for hr B – or Hr B – phenotype should implement the molecular characterization of Rh genes." @default.
• W2087203476 created "2016-06-24" @default.
• W2087203476 creator A5024240092 @default.
• W2087203476 creator A5051991048 @default.
• W2087203476 creator A5052450042 @default.
• W2087203476 creator A5062988327 @default.
• W2087203476 creator A5071971701 @default.
• W2087203476 creator A5072324110 @default.
• W2087203476 creator A5075760802 @default.
• W2087203476 creator A5078440038 @default.
• W2087203476 creator A5080994511 @default.
• W2087203476 date "2009-02-13" @default.
• W2087203476 modified "2023-10-09" @default.
• W2087203476 title "Heterogeneous molecular background of the weak C, VS+, hr^B-, Hr^B- phenotype in black persons" @default.
• W2087203476 cites W115901645 @default.
• W2087203476 cites W1980985575 @default.
• W2087203476 cites W1981386817 @default.
• W2087203476 cites W1994687461 @default.
• W2087203476 cites W2027919168 @default.
• W2087203476 cites W2066481736 @default.
• W2087203476 cites W2082172591 @default.
• W2087203476 cites W2101273232 @default.
• W2087203476 cites W2114183228 @default.
• W2087203476 cites W2126956249 @default.
• W2087203476 cites W2135496262 @default.
• W2087203476 cites W2135799217 @default.
• W2087203476 cites W2143202485 @default.
• W2087203476 cites W2147921835 @default.
• W2087203476 cites W2406729844 @default.
• W2087203476 cites W2411816909 @default.
• W2087203476 cites W2412920879 @default.
• W2087203476 cites W2412927650 @default.
• W2087203476 cites W947450170 @default.
• W2087203476 doi "https://doi.org/10.1111/j.1537-2995.2008.02005.x" @default.
• W2087203476 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19040491" @default.
• W2087203476 hasPublicationYear "2009" @default.
• W2087203476 type Work @default.
• W2087203476 sameAs 2087203476 @default.
• W2087203476 citedByCount "42" @default.
• W2087203476 countsByYear W20872034762012 @default.
• W2087203476 countsByYear W20872034762013 @default.
• W2087203476 countsByYear W20872034762014 @default.
• W2087203476 countsByYear W20872034762015 @default.
• W2087203476 countsByYear W20872034762016 @default.
• W2087203476 countsByYear W20872034762017 @default.
• W2087203476 countsByYear W20872034762018 @default.
• W2087203476 countsByYear W20872034762020 @default.
• W2087203476 countsByYear W20872034762021 @default.
• W2087203476 countsByYear W20872034762022 @default.
• W2087203476 countsByYear W20872034762023 @default.
• W2087203476 crossrefType "journal-article" @default.
• W2087203476 hasAuthorship W2087203476A5024240092 @default.
• W2087203476 hasAuthorship W2087203476A5051991048 @default.
• W2087203476 hasAuthorship W2087203476A5052450042 @default.
• W2087203476 hasAuthorship W2087203476A5062988327 @default.
• W2087203476 hasAuthorship W2087203476A5071971701 @default.
• W2087203476 hasAuthorship W2087203476A5072324110 @default.
• W2087203476 hasAuthorship W2087203476A5075760802 @default.
• W2087203476 hasAuthorship W2087203476A5078440038 @default.
• W2087203476 hasAuthorship W2087203476A5080994511 @default.
• W2087203476 hasConcept C104317684 @default.
• W2087203476 hasConcept C127716648 @default.
• W2087203476 hasConcept C147483822 @default.
• W2087203476 hasConcept C153911025 @default.
• W2087203476 hasConcept C17757408 @default.
• W2087203476 hasConcept C180754005 @default.
• W2087203476 hasConcept C197754878 @default.
• W2087203476 hasConcept C36823959 @default.
• W2087203476 hasConcept C54355233 @default.
• W2087203476 hasConcept C86803240 @default.
• W2087203476 hasConceptScore W2087203476C104317684 @default.
• W2087203476 hasConceptScore W2087203476C127716648 @default.
• W2087203476 hasConceptScore W2087203476C147483822 @default.
• W2087203476 hasConceptScore W2087203476C153911025 @default.
• W2087203476 hasConceptScore W2087203476C17757408 @default.
• W2087203476 hasConceptScore W2087203476C180754005 @default.
• W2087203476 hasConceptScore W2087203476C197754878 @default.
• W2087203476 hasConceptScore W2087203476C36823959 @default.
• W2087203476 hasConceptScore W2087203476C54355233 @default.
• W2087203476 hasConceptScore W2087203476C86803240 @default.
• W2087203476 hasIssue "3" @default.
• W2087203476 hasLocation W20872034761 @default.
• W2087203476 hasLocation W20872034762 @default.
• W2087203476 hasOpenAccess W2087203476 @default.
• W2087203476 hasPrimaryLocation W20872034761 @default.
• W2087203476 hasRelatedWork W1995266986 @default.
• W2087203476 hasRelatedWork W2023179002 @default.
• W2087203476 hasRelatedWork W2038017527 @default.
• W2087203476 hasRelatedWork W2094635246 @default.
• W2087203476 hasRelatedWork W2352780564 @default.
• W2087203476 hasRelatedWork W2398263405 @default.
• W2087203476 hasRelatedWork W2951456844 @default.
• W2087203476 hasRelatedWork W3146762847 @default.
• W2087203476 hasRelatedWork W4242979853 @default.
• W2087203476 hasRelatedWork W70397127 @default.
• W2087203476 hasVolume "49" @default.
• W2087203476 isParatext "false" @default.
• W2087203476 isRetracted "false" @default.

• next