Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087218963> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2087218963 abstract "This study compares several methods for diagnosing susceptibility to malignant hyperthermia, using two groups of Poland China swine narrowly defined as genetically susceptible or normal (five pigs each) depending respectively on their response to halothane or to halothane and succinylcholine. Vastus medialis muscle biopsies were excised under thiopental-N2O-O2 anesthesia and used for examination of (1) contracture responses to halothane, (2) contracture responses to caffeine and halothane-caffeine, and (3) adenosine triphosphate (ATP) depletion with and without halothane. All studies were performed in organ baths at 37 C. Halothane alone produced contractures in two susceptible and one normal preparation; caffeine always produced a contracture at lower concentrations in susceptible muscle; caffeine-halothane contractures in susceptible muscle occurred at lower mean caffeine concentrations, but there was some overlap of individual values; mean ATP depletion was greater in susceptible muscle, but with considerable overlap. Comparisons with the findings of others were hampered by use of absolute rather than comparative values for tension, e.g., grams, rather than grams per cross-sectional area or fraction of peak tension. Examination of the complete dose-response curve provided the best comparative information and caffeine was the consistent predictor of susceptibility." @default.
- W2087218963 created "2016-06-24" @default.
- W2087218963 creator A5029538384 @default.
- W2087218963 date "1979-09-01" @default.
- W2087218963 modified "2023-10-18" @default.
- W2087218963 title "Muscle Contractures and Adenosine Triphosphate Depletion in Porcine Malignant Hyperthermia" @default.
- W2087218963 doi "https://doi.org/10.1213/00000539-197909000-00004" @default.
- W2087218963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/573559" @default.
- W2087218963 hasPublicationYear "1979" @default.
- W2087218963 type Work @default.
- W2087218963 sameAs 2087218963 @default.
- W2087218963 citedByCount "8" @default.
- W2087218963 countsByYear W20872189632018 @default.
- W2087218963 crossrefType "journal-article" @default.
- W2087218963 hasAuthorship W2087218963A5029538384 @default.
- W2087218963 hasConcept C105702510 @default.
- W2087218963 hasConcept C126322002 @default.
- W2087218963 hasConcept C127607297 @default.
- W2087218963 hasConcept C141071460 @default.
- W2087218963 hasConcept C2776050358 @default.
- W2087218963 hasConcept C2776932660 @default.
- W2087218963 hasConcept C2776937108 @default.
- W2087218963 hasConcept C2776991684 @default.
- W2087218963 hasConcept C2778500429 @default.
- W2087218963 hasConcept C2778575482 @default.
- W2087218963 hasConcept C2779564974 @default.
- W2087218963 hasConcept C42219234 @default.
- W2087218963 hasConcept C71924100 @default.
- W2087218963 hasConceptScore W2087218963C105702510 @default.
- W2087218963 hasConceptScore W2087218963C126322002 @default.
- W2087218963 hasConceptScore W2087218963C127607297 @default.
- W2087218963 hasConceptScore W2087218963C141071460 @default.
- W2087218963 hasConceptScore W2087218963C2776050358 @default.
- W2087218963 hasConceptScore W2087218963C2776932660 @default.
- W2087218963 hasConceptScore W2087218963C2776937108 @default.
- W2087218963 hasConceptScore W2087218963C2776991684 @default.
- W2087218963 hasConceptScore W2087218963C2778500429 @default.
- W2087218963 hasConceptScore W2087218963C2778575482 @default.
- W2087218963 hasConceptScore W2087218963C2779564974 @default.
- W2087218963 hasConceptScore W2087218963C42219234 @default.
- W2087218963 hasConceptScore W2087218963C71924100 @default.
- W2087218963 hasLocation W20872189631 @default.
- W2087218963 hasLocation W20872189632 @default.
- W2087218963 hasOpenAccess W2087218963 @default.
- W2087218963 hasPrimaryLocation W20872189631 @default.
- W2087218963 hasRelatedWork W1966678582 @default.
- W2087218963 hasRelatedWork W1969898036 @default.
- W2087218963 hasRelatedWork W2054909191 @default.
- W2087218963 hasRelatedWork W2087218963 @default.
- W2087218963 hasRelatedWork W2130848429 @default.
- W2087218963 hasRelatedWork W2133715259 @default.
- W2087218963 hasRelatedWork W2398930276 @default.
- W2087218963 hasRelatedWork W44108151 @default.
- W2087218963 hasRelatedWork W74012194 @default.
- W2087218963 hasRelatedWork W149189570 @default.
- W2087218963 isParatext "false" @default.
- W2087218963 isRetracted "false" @default.
- W2087218963 magId "2087218963" @default.
- W2087218963 workType "article" @default.