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- W2087251224 abstract "We examined whether behavioral sensitization to amphetamine is associated with redistribution of glutamate receptors (GluR) in the rat nucleus accumbens (NAc) or dorsolateral striatum (DLSTR). Following repeated amphetamine treatment and 21 days of withdrawal, surface and intracellular levels of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) or NMDA receptor subunits were determined using a protein cross-linking assay. In contrast to our previous results in cocaine-sensitized rats, we did not observe redistribution of GluR1 or GluR2 to the cell surface in the NAc after amphetamine withdrawal, although a small increase in total GluR1 was found in the shell subregion. Nor did we observe activation of signaling pathways associated with cocaine-induced AMPA receptor trafficking or changes in NMDA receptor subunits. No significant changes were observed in the DLSTR. We also investigated the effect of administering a challenge injection of amphetamine to amphetamine-sensitized rats 24 h prior to biochemical analysis based on prior studies showing that cocaine challenge decreases AMPA receptor surface expression in the NAc of cocaine-sensitized rats. GluR1 and GluR2 were not significantly altered in either NAc or DLSTR, although a modest effect on GluR3 cannot be ruled out. Our results suggest that glutamate transmission in the NAc is dramatically different in rats sensitized to amphetamine versus cocaine." @default.
- W2087251224 created "2016-06-24" @default.
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- W2087251224 date "2009-03-09" @default.
- W2087251224 modified "2023-10-10" @default.
- W2087251224 title "Behavioral sensitization to amphetamine is not accompanied by changes in glutamate receptor surface expression in the rat nucleus accumbens" @default.
- W2087251224 cites W1503817558 @default.
- W2087251224 cites W1598659526 @default.
- W2087251224 cites W1604918007 @default.
- W2087251224 cites W1604957308 @default.
- W2087251224 cites W1775749144 @default.
- W2087251224 cites W1788048136 @default.
- W2087251224 cites W1873552451 @default.
- W2087251224 cites W1902584234 @default.
- W2087251224 cites W1972949334 @default.
- W2087251224 cites W1974998836 @default.
- W2087251224 cites W1976097422 @default.
- W2087251224 cites W1977077283 @default.
- W2087251224 cites W1980571433 @default.
- W2087251224 cites W1981730180 @default.
- W2087251224 cites W1983869923 @default.
- W2087251224 cites W1985484876 @default.
- W2087251224 cites W1986295217 @default.
- W2087251224 cites W1990572333 @default.
- W2087251224 cites W1990738732 @default.
- W2087251224 cites W1995680954 @default.
- W2087251224 cites W1996058486 @default.
- W2087251224 cites W2000340064 @default.
- W2087251224 cites W2009243814 @default.
- W2087251224 cites W2009429333 @default.
- W2087251224 cites W2014943258 @default.
- W2087251224 cites W2015701831 @default.
- W2087251224 cites W2016899263 @default.
- W2087251224 cites W2017277436 @default.
- W2087251224 cites W2019591259 @default.
- W2087251224 cites W2019636996 @default.
- W2087251224 cites W2027436298 @default.
- W2087251224 cites W2027445806 @default.
- W2087251224 cites W2037836204 @default.
- W2087251224 cites W2038071695 @default.
- W2087251224 cites W2041018266 @default.
- W2087251224 cites W2044600697 @default.
- W2087251224 cites W2045572233 @default.
- W2087251224 cites W2045846055 @default.
- W2087251224 cites W2047535883 @default.
- W2087251224 cites W2049683554 @default.
- W2087251224 cites W2050449932 @default.
- W2087251224 cites W2052329772 @default.
- W2087251224 cites W2052415426 @default.
- W2087251224 cites W2053748471 @default.
- W2087251224 cites W2054749214 @default.
- W2087251224 cites W2056607057 @default.
- W2087251224 cites W2057855503 @default.
- W2087251224 cites W2060736787 @default.
- W2087251224 cites W2066358338 @default.
- W2087251224 cites W2070002407 @default.
- W2087251224 cites W2071770303 @default.
- W2087251224 cites W2079311820 @default.
- W2087251224 cites W2079872157 @default.
- W2087251224 cites W2080055692 @default.
- W2087251224 cites W2083664551 @default.
- W2087251224 cites W2087288531 @default.
- W2087251224 cites W2089576439 @default.
- W2087251224 cites W2090599369 @default.
- W2087251224 cites W2097872145 @default.
- W2087251224 cites W2100579958 @default.
- W2087251224 cites W2102754843 @default.
- W2087251224 cites W2102864812 @default.
- W2087251224 cites W2104425131 @default.
- W2087251224 cites W2106862702 @default.
- W2087251224 cites W2112824246 @default.
- W2087251224 cites W2120077675 @default.
- W2087251224 cites W2122269460 @default.
- W2087251224 cites W2122916434 @default.
- W2087251224 cites W2128574573 @default.
- W2087251224 cites W2128969914 @default.
- W2087251224 cites W2136550122 @default.
- W2087251224 cites W2137340269 @default.
- W2087251224 cites W2137576981 @default.
- W2087251224 cites W2143053050 @default.
- W2087251224 cites W2145000368 @default.
- W2087251224 cites W2152696387 @default.
- W2087251224 cites W2163408424 @default.
- W2087251224 cites W2165510883 @default.
- W2087251224 cites W2166208293 @default.
- W2087251224 cites W2169765156 @default.
- W2087251224 cites W2169959530 @default.
- W2087251224 cites W4240874525 @default.
- W2087251224 cites W4246659915 @default.
- W2087251224 doi "https://doi.org/10.1111/j.1471-4159.2009.05911.x" @default.
- W2087251224 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2723058" @default.
- W2087251224 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19183251" @default.
- W2087251224 hasPublicationYear "2009" @default.
- W2087251224 type Work @default.