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• W2087272017 endingPage "4913" @default.
• W2087272017 startingPage "4907" @default.
• W2087272017 abstract "ABSTRACT We investigated the in vitro RNA dimerization properties of the untranslated leader RNA derived from human immunodeficiency virus type 1 variants circulating in an individual with a low viral load and slow disease progression. The leader sequences of these viruses contain highly unusual polymorphisms within the dimerization initiation site (DIS): an insert that abolishes dimerization and a compensatory substitution. The dimerization of leader RNA from late stages of infection is further improved by additional mutations outside the DIS motif that facilitate a secondary structure switch from a dimerization-incompetent to a dimerization-competent RNA conformation." @default.
• W2087272017 created "2016-06-24" @default.
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• W2087272017 date "2004-05-01" @default.
• W2087272017 modified "2023-09-24" @default.
• W2087272017 title "A Human Immunodeficiency Virus Type 1-Infected Individual with Low Viral Load Harbors a Virus Variant That Exhibits an In Vitro RNA Dimerization Defect" @default.
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• W2087272017 doi "https://doi.org/10.1128/jvi.78.9.4907-4913.2004" @default.
• W2087272017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/387700" @default.
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