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- W2087279999 abstract "There is evidence that 2′-deoxycoformycin (DCF) functions as a differentiating agent. We examined the effects of DCF on the differentiation of HL-60 cells, a standard model of leukemic cell differentiation. DCF did not induce morphologic or histochemical evidence of differentiation, nor did it interact with retinoic acid, 1,25-dihydroxyvitamin D3, or interferon-gamma in inducing differentiation. Furthermore, DCF and agents that differentiated HL-60 cells had opposing effects on adenosine deaminase and 2′, 5′-oligoadenylate synthetase activity." @default.
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- W2087279999 date "1990-04-01" @default.
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- W2087279999 title "Effects of 2′-deoxycoformycin on hl-60 cell differentiation, adenosine deaminase, and oligoadenylate synthetase" @default.
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- W2087279999 doi "https://doi.org/10.1002/ajh.2830330412" @default.
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