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- W2087307959 abstract "Abstract Pituitary GnRH receptor concentrations were measured during different stages of continuous infusion with a low dose of GnRH in progesterone-treated seasonally anoestrous ewes. A total of 32 ewes were randomly divided into four equal-sized groups (eight ewes per group) and were slaughtered before and 12, 24 or 96 h after the start of GnRH infusion (250 ng h−1) administered subcutaneously by osmotic mini pumps. Ewes slaughtered after 12 and 24 h of GnRH infusion had a significantly higher pituitary GnRH binding content compared with either control ewes or those slaughtered after 96 h GnRH infusion. A significant positive correlation was observed between mean plasma LH concentration in the 6 h period before slaughter and pituitary GnRH binding. These data demonstrate that, in the short term, GnRH infusion increases both plasma LH concentrations and pituitary GnRH binding, and that the failure of GnRH infusion to maintain pituitary responses thereafter is associated with a decrease in pituitary GnRH receptor content." @default.
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- W2087307959 date "1991-05-01" @default.
- W2087307959 modified "2023-09-27" @default.
- W2087307959 title "Pituitary GnRH receptor dynamics during continuous infusion of a low dose of GnRH in seasonally anoestrous ewes" @default.
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- W2087307959 doi "https://doi.org/10.1016/0378-4320(91)90006-l" @default.
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