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• W2087320843 abstract "Administration of somatostatin to rats induced a transient reduction of serum levels of deoxyribonuclease I (DNase I) activity in a dose-dependent manner, followed by a substantial decrease of DNase I activity in the lower gut. Activity in the parotid gland, liver, and kidney did not change. Real-time PCR analysis of the DNase I gene transcript in ileum indicated that the decrease was due to down-regulation of gene expression. Based on these responses, rat tissues expressing DNase I could be classified into two types, somatostatin-sensitive and somatostatin-resistant, and the level of DNase I activity in the lower gut seems to be controlled by somatostatin." @default.
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• W2087320843 date "2001-05-01" @default.
• W2087320843 modified "2023-09-25" @default.
• W2087320843 title "Tissue-Specific in Vivo Inhibition of DNase I Gene Expression by Somatostatin" @default.
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• W2087320843 doi "https://doi.org/10.1006/bbrc.2001.4770" @default.
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