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• W2087335931 abstract "I will be the first to admit it. Somewhere along the line, I, like many clinician–educators, stopped reading JID regularly. Most of us read JID at one point (usually during residency, when it was required reading for journal club). As we get lost in clinical medicine and further removed from our basic science lectures, it becomes more difficult to keep up with the ever-increasing body of scientific knowledge that is the basis of our challenging specialty. And so the JID is left on the shelf in the wrapper—assuming we even still subscribe—and our scientific literacy shrinks away. The problem with this is that our field is strongly based in science, and our scientific discoveries keep us moving forward. Just in recent years, basic science discovery has provided breakthroughs as diverse as the first effective medical therapies for metastatic melanoma and basal cell carcinoma based on identifying key oncogenic mutations and intracellular signaling pathways, and multiple nonscarring laser therapies based on a detailed appreciation of skin optics. Clinical research, such as randomized controlled trials and systematic reviews, helps determine the direction of care we provide every day. We use these advances to benefit our patients, but often we have only a crude understanding of the science that underlies them. We, as dermatologists, therefore risk being reduced to simple technicians, employing tools that we barely understand. An even greater potential tragedy is that, in being removed from the scientific base of our field, we clinicians lose the opportunity to provide critical feedback to our laboratory-based investigators about unmet needs that might be addressed with cutting-edge technology. Those of us working in the medical trenches actually understand the diseases much better than do many of our laboratory-based colleagues; it is our responsibility to help bridge the translational gap that is essential to fully understand and manage skin diseases. With welcome support from the American Academy of Dermatology in the form of a small Program for Innovative Continuing Medical Education in Dermatology (PICMED) Educational Grant, we have undertaken a pilot project to increase JID's relevance and accessibility to trainees and practicing dermatologists by creating new online features that will help to demystify science and allow us to reconnect with our scientific base. Enter “Research Techniques Made Simple” (RTMS). This pilot project consists of 10 brief, online articles; the first appears in conjunction with this month's issue. Each article will explain in simple terms a widely used laboratory or clinical-research technique that has been employed in recent scientific (and often also clinical) publications. The goal of this project is to help those without a strong background in research visualize and understand the basics of a given technique. We want to help readers feel comfortable reading articles that utilize the technique and to better understand the results and outcomes of the studies. We have asked authors of the RTMS articles to explain the benefits and limitations of a particular technique and to discuss when and why it might be employed. They will use several recent JID articles to highlight their discussions. To produce the monthly articles, we are assembling 10 teams, each consisting of two to four individuals (ideally, a trainee or two, a clinician–educator, and a science content expert), who will work together to ensure that the material is both scientifically accurate and meaningful to readers at many different levels of scientific understanding. Because we anticipate that these articles will be useful to residency training programs (many of which do not include basic scientists among their faculty), downloadable PowerPoint slides, appropriate for use in journal clubs or other didactic sessions, will accompany each article. All articles will be reviewed by the JID Editorial Board and, once accepted, published online, where they will be part of the JID archive. In our first article, Jahan-Tigh and colleagues beautifully explain flow cytometry and guide readers through data that otherwise might be daunting to the uninitiated (doi:10.1038/jid.2012.282). I promise that anyone who reads their article will never again fear a scatter plot. I offer particular thanks to this team for working on short notice and for being willing and able to make changes as the project evolved. Future topics include confocal microscopy, meta-analysis, and immunofluorescence techniques. I urge you to read them, share them with trainees and colleagues, and give me your feedback by e-mail at [email protected] Will “Research Techniques Made Simple” create the next generation of basic scientists? Maybe not. But we hope the series will remind us that we all have a bit of scientist in us." @default.
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• W2087335931 date "2012-10-01" @default.
• W2087335931 modified "2023-09-30" @default.
• W2087335931 title "Confessions of a JID -Lapsed Clinician–Educator" @default.
• W2087335931 doi "https://doi.org/10.1038/jid.2012.277" @default.
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