FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087355390> ?p ?o ?g. }

• W2087355390 endingPage "992" @default.
• W2087355390 startingPage "971" @default.
• W2087355390 abstract "This study aimed to evaluate the crystalline and amorphous carvedilol along with their lipidic mixtures using various instrumental techniques and to use response surface methodology in conjunction with factorial design to establish the functional relationships between operating variables (capmul GMS 50 K and cremophor RH 40). The response variables selected are spectroscopic absorbance (Y 1), mean particle size in distilled water (Y 2) and in phosphate buffer pH 6.8 (Y 3), polydispersibility index (PDI) (Y 4) and zeta potential (Y 5). The optimal formulations of crystalline and amorphous carvedilol-loaded nanoemulsions were composed of fixed levels, −0.41 and −0.42, of capmul GMS 50 K and cremophor RH 40, respectively. The predicted and observed values of Y 1–Y 5 for blank nanoemulsions showed the percentage bias error of −12.12%, −10.25%, −18.47%, +14.81 and −2.89, respectively. The bias percent ranged between −2.70% and −29.41% for the responses Y 1–Y 4 for both crystalline and amorphous carvedilol-loaded nanoemulsions, indicating high degree of prognosis. However, the bias percent values for the response variable Y 5 were 294.2% and 262.6%, for the crystalline and amorphous carvedilol-loaded nanoemulsions, respectively, possibly due to cationisation of emulsion droplets. The transmission electron microscopy of selected optimal nanoemulsions showed the spherical shape of globules with no signs of coalescence and precipitation of drug. This study demonstrates the use of factorial design for the preparation of nanoemulsions of crystalline and amorphous carvedilol. The desirable goals can be obtained by systematic formulation approach in the shortest possible time." @default.
• W2087355390 created "2016-06-24" @default.
• W2087355390 creator A5008685454 @default.
• W2087355390 creator A5012552552 @default.
• W2087355390 creator A5055372327 @default.
• W2087355390 creator A5078821399 @default.
• W2087355390 creator A5082315966 @default.
• W2087355390 creator A5087888100 @default.
• W2087355390 date "2012-05-18" @default.
• W2087355390 modified "2023-10-17" @default.
• W2087355390 title "Crystalline and amorphous carvedilol-loaded nanoemulsions: formulation optimisation using response surface methodology" @default.
• W2087355390 cites W1964579411 @default.
• W2087355390 cites W1974008347 @default.
• W2087355390 cites W1981081691 @default.
• W2087355390 cites W1984323776 @default.
• W2087355390 cites W1999026740 @default.
• W2087355390 cites W2000505705 @default.
• W2087355390 cites W2001328146 @default.
• W2087355390 cites W2016532277 @default.
• W2087355390 cites W2021721280 @default.
• W2087355390 cites W2036203558 @default.
• W2087355390 cites W2038365601 @default.
• W2087355390 cites W2039499240 @default.
• W2087355390 cites W2044594845 @default.
• W2087355390 cites W2045222790 @default.
• W2087355390 cites W2061263372 @default.
• W2087355390 cites W2065007687 @default.
• W2087355390 cites W2072377888 @default.
• W2087355390 cites W2077594374 @default.
• W2087355390 cites W2078814811 @default.
• W2087355390 cites W2090729175 @default.
• W2087355390 cites W2092301054 @default.
• W2087355390 cites W2101785560 @default.
• W2087355390 cites W2107191669 @default.
• W2087355390 cites W2149111315 @default.
• W2087355390 cites W2155751766 @default.
• W2087355390 cites W2170366782 @default.
• W2087355390 cites W2326508838 @default.
• W2087355390 cites W4375819215 @default.
• W2087355390 doi "https://doi.org/10.1080/17458080.2011.630037" @default.
• W2087355390 hasPublicationYear "2012" @default.
• W2087355390 type Work @default.
• W2087355390 sameAs 2087355390 @default.
• W2087355390 citedByCount "11" @default.
• W2087355390 countsByYear W20873553902013 @default.
• W2087355390 countsByYear W20873553902015 @default.
• W2087355390 countsByYear W20873553902016 @default.
• W2087355390 countsByYear W20873553902019 @default.
• W2087355390 countsByYear W20873553902020 @default.
• W2087355390 countsByYear W20873553902021 @default.
• W2087355390 countsByYear W20873553902023 @default.
• W2087355390 crossrefType "journal-article" @default.
• W2087355390 hasAuthorship W2087355390A5008685454 @default.
• W2087355390 hasAuthorship W2087355390A5012552552 @default.
• W2087355390 hasAuthorship W2087355390A5055372327 @default.
• W2087355390 hasAuthorship W2087355390A5078821399 @default.
• W2087355390 hasAuthorship W2087355390A5082315966 @default.
• W2087355390 hasAuthorship W2087355390A5087888100 @default.
• W2087355390 hasConcept C105795698 @default.
• W2087355390 hasConcept C113196181 @default.
• W2087355390 hasConcept C121332964 @default.
• W2087355390 hasConcept C127413603 @default.
• W2087355390 hasConcept C149792144 @default.
• W2087355390 hasConcept C150077022 @default.
• W2087355390 hasConcept C155672457 @default.
• W2087355390 hasConcept C169222746 @default.
• W2087355390 hasConcept C171250308 @default.
• W2087355390 hasConcept C185592680 @default.
• W2087355390 hasConcept C187530423 @default.
• W2087355390 hasConcept C192562407 @default.
• W2087355390 hasConcept C2778123984 @default.
• W2087355390 hasConcept C2779429693 @default.
• W2087355390 hasConcept C33923547 @default.
• W2087355390 hasConcept C42360764 @default.
• W2087355390 hasConcept C43617362 @default.
• W2087355390 hasConcept C56052488 @default.
• W2087355390 hasConcept C58226133 @default.
• W2087355390 hasConcept C8010536 @default.
• W2087355390 hasConcept C86181022 @default.
• W2087355390 hasConcept C87355193 @default.
• W2087355390 hasConceptScore W2087355390C105795698 @default.
• W2087355390 hasConceptScore W2087355390C113196181 @default.
• W2087355390 hasConceptScore W2087355390C121332964 @default.
• W2087355390 hasConceptScore W2087355390C127413603 @default.
• W2087355390 hasConceptScore W2087355390C149792144 @default.
• W2087355390 hasConceptScore W2087355390C150077022 @default.
• W2087355390 hasConceptScore W2087355390C155672457 @default.
• W2087355390 hasConceptScore W2087355390C169222746 @default.
• W2087355390 hasConceptScore W2087355390C171250308 @default.
• W2087355390 hasConceptScore W2087355390C185592680 @default.
• W2087355390 hasConceptScore W2087355390C187530423 @default.
• W2087355390 hasConceptScore W2087355390C192562407 @default.
• W2087355390 hasConceptScore W2087355390C2778123984 @default.
• W2087355390 hasConceptScore W2087355390C2779429693 @default.
• W2087355390 hasConceptScore W2087355390C33923547 @default.
• W2087355390 hasConceptScore W2087355390C42360764 @default.
• W2087355390 hasConceptScore W2087355390C43617362 @default.
• W2087355390 hasConceptScore W2087355390C56052488 @default.

• next