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• W2087366831 abstract "Significance An important goal of cancer biology is to identify molecular differences between normal and cancer cells. Accordingly, many large-scale initiatives to characterize both solid and liquid tumor samples with genomics technologies are currently underway. Here, we show that standard blood collection procedures cause rapid changes to the transcriptomes of hematopoietic cells. The resulting transcriptional and posttranscriptional artifacts are visible in most published leukemia genomics datasets and hinder the identification and interpretation of cancer-specific alterations." @default.
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• W2087366831 date "2014-11-10" @default.
• W2087366831 modified "2023-10-12" @default.
• W2087366831 title "Sample processing obscures cancer-specific alterations in leukemic transcriptomes" @default.
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• W2087366831 doi "https://doi.org/10.1073/pnas.1413374111" @default.
• W2087366831 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4250124" @default.
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