FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087367348> ?p ?o ?g. }

• W2087367348 endingPage "506" @default.
• W2087367348 startingPage "498" @default.
• W2087367348 abstract "Mutations in the X-linked MECP2 gene are the primary cause of the severe autism spectrum disorder RTT (Rett syndrome). Deletion of Mecp2 in mice recapitulates many of the overt neurological features seen in humans, and the delayed onset of symptoms is accompanied by deficits in neuronal morphology and synaptic physiology. Recent evidence suggests that reactivation of endogenous Mecp2 in young and adult mice can reverse aspects of RTT-like pathology. In the current perspective, we discuss these findings as well as other genetic, pharmacological and environmental interventions that attempt phenotypic rescue in RTT. We believe these studies provide valuable insights into the tractability of RTT and related conditions and are useful pointers for the development of future therapeutic strategies." @default.
• W2087367348 created "2016-06-24" @default.
• W2087367348 creator A5000905868 @default.
• W2087367348 creator A5017860049 @default.
• W2087367348 creator A5052906260 @default.
• W2087367348 date "2010-03-22" @default.
• W2087367348 modified "2023-10-15" @default.
• W2087367348 title "Reversibility of functional deficits in experimental models of Rett syndrome" @default.
• W2087367348 cites W1488115555 @default.
• W2087367348 cites W1559742681 @default.
• W2087367348 cites W1964159332 @default.
• W2087367348 cites W1974814280 @default.
• W2087367348 cites W1975791071 @default.
• W2087367348 cites W1977569817 @default.
• W2087367348 cites W1978127185 @default.
• W2087367348 cites W1979223448 @default.
• W2087367348 cites W1981495424 @default.
• W2087367348 cites W1988559329 @default.
• W2087367348 cites W1988794993 @default.
• W2087367348 cites W1989779456 @default.
• W2087367348 cites W1991923036 @default.
• W2087367348 cites W1992168493 @default.
• W2087367348 cites W1992789817 @default.
• W2087367348 cites W1993341628 @default.
• W2087367348 cites W1993852989 @default.
• W2087367348 cites W1994210488 @default.
• W2087367348 cites W1994974752 @default.
• W2087367348 cites W1995058974 @default.
• W2087367348 cites W1995470989 @default.
• W2087367348 cites W1998448281 @default.
• W2087367348 cites W1999775510 @default.
• W2087367348 cites W2000313340 @default.
• W2087367348 cites W2001621733 @default.
• W2087367348 cites W2001657520 @default.
• W2087367348 cites W2001936578 @default.
• W2087367348 cites W2008964449 @default.
• W2087367348 cites W2011493536 @default.
• W2087367348 cites W2014408116 @default.
• W2087367348 cites W2014872693 @default.
• W2087367348 cites W2015748323 @default.
• W2087367348 cites W2017990561 @default.
• W2087367348 cites W2019435101 @default.
• W2087367348 cites W2021540664 @default.
• W2087367348 cites W2021996855 @default.
• W2087367348 cites W2033609439 @default.
• W2087367348 cites W2035090622 @default.
• W2087367348 cites W2045042214 @default.
• W2087367348 cites W2046022138 @default.
• W2087367348 cites W2046459630 @default.
• W2087367348 cites W2053364149 @default.
• W2087367348 cites W2053665741 @default.
• W2087367348 cites W2054282296 @default.
• W2087367348 cites W2055481919 @default.
• W2087367348 cites W2055911520 @default.
• W2087367348 cites W2056111473 @default.
• W2087367348 cites W2059449250 @default.
• W2087367348 cites W2062872787 @default.
• W2087367348 cites W2067004457 @default.
• W2087367348 cites W2067570041 @default.
• W2087367348 cites W2068674192 @default.
• W2087367348 cites W2069194632 @default.
• W2087367348 cites W2077273976 @default.
• W2087367348 cites W2082405299 @default.
• W2087367348 cites W2083421199 @default.
• W2087367348 cites W2083657788 @default.
• W2087367348 cites W2084889756 @default.
• W2087367348 cites W2085811948 @default.
• W2087367348 cites W2086445418 @default.
• W2087367348 cites W2089577924 @default.
• W2087367348 cites W2091978449 @default.
• W2087367348 cites W2092491756 @default.
• W2087367348 cites W2092790576 @default.
• W2087367348 cites W2094841633 @default.
• W2087367348 cites W2108470366 @default.
• W2087367348 cites W2108921991 @default.
• W2087367348 cites W2115301408 @default.
• W2087367348 cites W2125603023 @default.
• W2087367348 cites W2127311839 @default.
• W2087367348 cites W2130690907 @default.
• W2087367348 cites W2145476724 @default.
• W2087367348 cites W2145746159 @default.
• W2087367348 cites W2149631083 @default.
• W2087367348 cites W2151501729 @default.
• W2087367348 cites W2152497434 @default.
• W2087367348 cites W2152668149 @default.
• W2087367348 cites W2155388782 @default.
• W2087367348 cites W2156696931 @default.
• W2087367348 cites W2164502083 @default.
• W2087367348 cites W2168126378 @default.
• W2087367348 cites W2171657985 @default.
• W2087367348 cites W2397166584 @default.
• W2087367348 doi "https://doi.org/10.1042/bst0380498" @default.
• W2087367348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20298210" @default.
• W2087367348 hasPublicationYear "2010" @default.
• W2087367348 type Work @default.
• W2087367348 sameAs 2087367348 @default.
• W2087367348 citedByCount "60" @default.
• W2087367348 countsByYear W20873673482012 @default.

• next