FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2087372716> ?p ?o ?g. }

• W2087372716 endingPage "360" @default.
• W2087372716 startingPage "355" @default.
• W2087372716 abstract "The likelihood of radiation pneumonitis and factors associated with its development in breast cancer patients treated with conservative surgery and radiation therapy have not been well established. To assess these, we retrospectively reviewed 1624 patients treated between 1968 and 1985. Median follow-up for patients without local or distant failure was 77 months. Patients were treated with either tangential fields alone (n = 508) or tangents with a third field to the supraclavicular (SC) or SC-axillary (AX) region (n = 1116). Lung volume treated in the tangential fields was generally limited by keeping the perpendicular distance (demagnified) at the isocenter from the deep field edges to the posterior chest wall (CLD) to 3 cm or less. Seventeen patients with radiation pneumonitis were identified (1.0%). Radiation pneumonitis was diagnosed when patients presented with cough (15/17, 88%), fever (9/17,53%), and/or dyspnea (6/17,35%) and radiographic changes (17/17) following completion of RT. Radiographic infiltrates corresponded to treatment portals in all patients, and in 12 of the 17 patients, returned to baseline within 1–12 months. Five patients had permanent scarring on chest X ray. No patient had late or persistent pulmonary symptoms. The incidence of radiation pneumonitis was correlated with the combined use of chemotherapy (CT) and a third field. Three percent (11/328) of patients treated with a 3-field technique who received chemotherapy developed radiation pneumonitis compared to 0.5% (6 of 1296) for all other patients (p = 0.0001). When patients reated with a 3-field technique received chemotherapy concurrently with radiation therapy, the incidence of radiation pneumonitis was 8.8% (8/92) compared with 1.3% (3/236) for those who received sequential chemotherapy and radiation therapy (p = 0.002). A casexontrol analysis was performed to determine if the volume of lung irradiated (as determined using central lung distance [CLD]) was related to the risk of developing radiation pneumonitis. Three control patients were matched to each case of radiation pneumonitis based on age, side of lesion, chemotherapy (including sequencing), use of a third field, and year treated. Lung volumes were similar in the radiation pneumonitis cases and controls. We conclude that radiation pneumonitis following conservative surgery and radiation therapy for breast cancer is a rare complication, and that it is more likely to occur in patients treated with both a 3-field technique and chemotherapy (particularly given concurrently with radiation therapy). Over the limited range of volumes treated, lung volume was not associated with an increased risk of radiation pneumonitis." @default.
• W2087372716 created "2016-06-24" @default.
• W2087372716 creator A5012874237 @default.
• W2087372716 creator A5013474509 @default.
• W2087372716 creator A5016407136 @default.
• W2087372716 creator A5021503571 @default.
• W2087372716 creator A5031157638 @default.
• W2087372716 creator A5078561959 @default.
• W2087372716 date "1991-07-01" @default.
• W2087372716 modified "2023-10-11" @default.
• W2087372716 title "Radiation pneumonitis in breast cancer patients treated with conservative surgery and radiation therapy" @default.
• W2087372716 cites W1502760568 @default.
• W2087372716 cites W1964624837 @default.
• W2087372716 cites W1975474349 @default.
• W2087372716 cites W1979786140 @default.
• W2087372716 cites W1988024604 @default.
• W2087372716 cites W1988245407 @default.
• W2087372716 cites W1990143374 @default.
• W2087372716 cites W1990635277 @default.
• W2087372716 cites W1998556278 @default.
• W2087372716 cites W1999156521 @default.
• W2087372716 cites W2001914827 @default.
• W2087372716 cites W2003707978 @default.
• W2087372716 cites W2015993287 @default.
• W2087372716 cites W2032142535 @default.
• W2087372716 cites W2042364872 @default.
• W2087372716 cites W2048438033 @default.
• W2087372716 cites W2056808991 @default.
• W2087372716 cites W2058007426 @default.
• W2087372716 cites W2073205845 @default.
• W2087372716 cites W2080416210 @default.
• W2087372716 cites W2082288366 @default.
• W2087372716 cites W2100329719 @default.
• W2087372716 cites W2121886805 @default.
• W2087372716 cites W4237048633 @default.
• W2087372716 doi "https://doi.org/10.1016/0360-3016(91)90782-y" @default.
• W2087372716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2061112" @default.
• W2087372716 hasPublicationYear "1991" @default.
• W2087372716 type Work @default.
• W2087372716 sameAs 2087372716 @default.
• W2087372716 citedByCount "395" @default.
• W2087372716 countsByYear W20873727162012 @default.
• W2087372716 countsByYear W20873727162013 @default.
• W2087372716 countsByYear W20873727162014 @default.
• W2087372716 countsByYear W20873727162015 @default.
• W2087372716 countsByYear W20873727162016 @default.
• W2087372716 countsByYear W20873727162017 @default.
• W2087372716 countsByYear W20873727162018 @default.
• W2087372716 countsByYear W20873727162019 @default.
• W2087372716 countsByYear W20873727162020 @default.
• W2087372716 countsByYear W20873727162021 @default.
• W2087372716 countsByYear W20873727162022 @default.
• W2087372716 countsByYear W20873727162023 @default.
• W2087372716 crossrefType "journal-article" @default.
• W2087372716 hasAuthorship W2087372716A5012874237 @default.
• W2087372716 hasAuthorship W2087372716A5013474509 @default.
• W2087372716 hasAuthorship W2087372716A5016407136 @default.
• W2087372716 hasAuthorship W2087372716A5021503571 @default.
• W2087372716 hasAuthorship W2087372716A5031157638 @default.
• W2087372716 hasAuthorship W2087372716A5078561959 @default.
• W2087372716 hasConcept C120665830 @default.
• W2087372716 hasConcept C121332964 @default.
• W2087372716 hasConcept C121608353 @default.
• W2087372716 hasConcept C126322002 @default.
• W2087372716 hasConcept C126838900 @default.
• W2087372716 hasConcept C141071460 @default.
• W2087372716 hasConcept C181401712 @default.
• W2087372716 hasConcept C2776694085 @default.
• W2087372716 hasConcept C2777714996 @default.
• W2087372716 hasConcept C2779524853 @default.
• W2087372716 hasConcept C2908954928 @default.
• W2087372716 hasConcept C2989005 @default.
• W2087372716 hasConcept C36454342 @default.
• W2087372716 hasConcept C509974204 @default.
• W2087372716 hasConcept C530470458 @default.
• W2087372716 hasConcept C61511704 @default.
• W2087372716 hasConcept C71924100 @default.
• W2087372716 hasConceptScore W2087372716C120665830 @default.
• W2087372716 hasConceptScore W2087372716C121332964 @default.
• W2087372716 hasConceptScore W2087372716C121608353 @default.
• W2087372716 hasConceptScore W2087372716C126322002 @default.
• W2087372716 hasConceptScore W2087372716C126838900 @default.
• W2087372716 hasConceptScore W2087372716C141071460 @default.
• W2087372716 hasConceptScore W2087372716C181401712 @default.
• W2087372716 hasConceptScore W2087372716C2776694085 @default.
• W2087372716 hasConceptScore W2087372716C2777714996 @default.
• W2087372716 hasConceptScore W2087372716C2779524853 @default.
• W2087372716 hasConceptScore W2087372716C2908954928 @default.
• W2087372716 hasConceptScore W2087372716C2989005 @default.
• W2087372716 hasConceptScore W2087372716C36454342 @default.
• W2087372716 hasConceptScore W2087372716C509974204 @default.
• W2087372716 hasConceptScore W2087372716C530470458 @default.
• W2087372716 hasConceptScore W2087372716C61511704 @default.
• W2087372716 hasConceptScore W2087372716C71924100 @default.
• W2087372716 hasIssue "2" @default.
• W2087372716 hasLocation W20873727161 @default.
• W2087372716 hasLocation W20873727162 @default.
• W2087372716 hasOpenAccess W2087372716 @default.

• next