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- W2087375462 abstract "The long history of neuroscience has accumulated information about numerous types of neurons in the brain of various organisms. Because such neurons have been reported in diverse publications without controlled format, it is not easy to keep track of all the known neurons in a particular nervous system. To address this issue we constructed an online database called Flybrain Neuron Database (Flybrain NDB), which serves as a platform to collect and provide information about all the types of neurons published so far in the brain of Drosophila melanogaster. Projection patterns of the identified neurons in diverse areas of the brain were recorded in a unified format, with text-based descriptions as well as images and movies wherever possible. In some cases projection sites and the distribution of the post- and presynaptic sites were determined with greater detail than described in the original publication. Information about the labeling patterns of various antibodies and expression driver strains to visualize identified neurons are provided as a separate sub-database. We also implemented a novel visualization tool with which users can interactively examine three-dimensional reconstruction of the confocal serial section images with desired viewing angles and cross sections. Comprehensive collection and versatile search function of the anatomical information reported in diverse publications make it possible to analyze possible connectivity between different brain regions. We analyzed the preferential connectivity among optic lobe layers and the plausible olfactory sensory map in the lateral horn to show the usefulness of such a database. J. Comp. Neurol. 519:807-833, 2011. © 2010 Wiley-Liss, Inc." @default.
- W2087375462 created "2016-06-24" @default.
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- W2087375462 date "2011-01-28" @default.
- W2087375462 modified "2023-10-18" @default.
- W2087375462 title "Flybrain neuron database: A comprehensive database system of the Drosophila brain neurons" @default.
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- W2087375462 doi "https://doi.org/10.1002/cne.22540" @default.
- W2087375462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21280038" @default.
- W2087375462 hasPublicationYear "2011" @default.
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